919 



Alkaptonuria, urine of, homogentisic 

 acid in, formula for, 504. 



synthesis of, Baumann and 

 Frankel, 504. 



Neubauer and Falta, 506. 



Osborne, 505. 



transformation of tyrosin to, 



507. 



isolation of substances in, 503. 



protocatechinic acid in, 503. 



pyrocatechol in, 503. 



substances in, 503. 



uroleucic acid in, 503. 

 Allantoin, formula for, 414. 



relation of, to uric acid, 414. 

 Allen method of starvation in diabetes, 



26. 



Alloxuric bases, 413. 



Alveolar COa tension, determination 

 of, 82. 



Ambard's coefficient of urea excretion, 

 358. 



Amino acid nitrogen, in urine, 

 amounts found by various investi- 

 gators, table, 475. 



Amino acids, leucin, in urine, 476. 



in nephritis, 331. 



tyrosin, in urine, 476. 



in urine, increased amount of, in 

 pathological conditions, or amino- 

 aciduria, 475. 



Aminoaciduria, conditions causing, 



476. 



Ammonia formation, 56, 66. 

 Ammonia and free acid, determination 



of excretion of, 83. 

 Amyotonia congenita, metabolism in, 



730. 



Anabolism, bone, 735. 

 Anaphylaxis, active, 197. 

 -anti-, 198. 



degrees of hypersensitiveness, non- 

 specific alteration of, 216. 



etiology of, 205. 



cellular and humoral theories, 



205. 

 evidence regarding theories of, 



206, 207. 

 intracellular theory, 206, 211. 



experimental, differentiated from 

 natural idiosyncrasies, 227. 



pathological physiology of, 198. 



blood and blood-forming or- 

 gans, 203. 



blood pressure, 201. 



capillaries, 201. 



cardiovascular mechanism, 

 201. 



Anaphylaxis, experimental, pathologi- 

 cal physiology of, in cat, 199. 

 -in dog, 199, 202. 



gastro-intestinal tract, 202. 



in guinea-pig, 199. 

 -heart, 202. 

 -liver, 203. 

 -lungs, 201. 



in man, 200. 



muscles, 204. 

 -in rabbit, 199. 



relationship of, to diseases in 

 man, 218. 



heat regulation in, 213. 



historical, 197. 



hypersensitiveness, degrees of, 224. 



variations in, 225. 

 -forms of, 222. 



materials producing, variety of, 



226. 



idiosyncrasies of, 222. 



natural, differentiated from ex- 

 perimental anaphylaxis, 227. 



introduction to, 197. 



metabolism in, asthma, 229. 



heat regulation, 213. 

 -protein, 209. 



respiratory, 212. 



urticaria, 229. 



multiple sensitizations, 227. 



non-specific alteration of the degrees 

 of hypersensitiveness, 216. 



passive, 197. 



pathological physiology of, in ex- 

 perimental anaphylaxis, 198. 



blood and blood-forming or- 

 gans, 203. 



blood pressure, 201. 



capillaries, 201. 



cardiovascular mechanism, 



201. 



- in cat, 199. 



in dog, 199, 202. 



gastro-intestinal tract, 202. 



in guinea pig, 199. 



-heart, 202. 

 -liver, 203. 



lungs, 201. 



in man, 200. 



muscles, 204. 



-in rabbit, 199. 



serum and cellular ferments, 214. 

 -pathology of, 208. 



phenomena of, 197. 



place of formation of poisonous sub- 

 stance which brings about anaphy- 

 lactic shock, 205. 



protein intoxication, 230. 



