C. REID. 163 



(2) Urine diastase. — In the absence of polyuria the diastatic index in the 

 majority of healthy individuals lies between 6 and 14. 



(3) Diastatic concentration factor. — The normal figure obtained lies in the 

 majority of cases between 20 and 30 with outside limits of about 15 to 40. 



Nephritic Subjects, etc. 



Numerous cases of nephritis mostly, of diabetes, arteriosclerosis, prostatic 

 enlargement, etc., were examined in the same way as the preceding normal 

 cases with a view to seeing whether there was any variation from the normal 

 diastatic concentration factor in renal disease. 



The results are shown in Table IX. 



Blood diastase. — High levels were found in a number of kidney conditions 

 such as acute nephritis, uraemia, cardio-renal cases with failing heart. In 

 addition, high levels were also found in 2 out of 5 diabetic cases and in 

 2 out of 4 cases of prostatic enlargement with retention of urine. 



Urine diastase. — High levels were found in acute nephritis and in cases of 

 cardio-renal disease showing failure of urinary secretion. Low levels were 

 found in many cases of chronic kidney disease and of prostatic enlargement 

 with retention. 



Diastatic concentration factor. — While the figures obtained in acute 

 nephritis were high, low figures were obtained in cases of chronic renal 

 disease, enlarged prostate and diabetes. 



Prostatic Cases. 



Table X shows the results obtained in four cases of prostatic enlargement 

 with retention of urine. 



Case. Age. Blood urea. Urine urea. B.D. U.D. D.C.F. Remarks. 



38 . 65 . 90 . — . 11-4 . 2.3-5. General condition fair. 



39 . 85 . 150 . r35% . 3 . <2 . Low . General condition poor; chronic 



ursemic state. 



40 . 79 . 60 . 1-2% . 7 . <2 . „ . Pus in urine ; clearing ; general 



condition improving. 



41 . 63 . 90 . 1"6% .16 . 6.7 . Stricture and enlarged prostate ; 



blood and pus in urine ; tongue 

 dry ; general condition poor. 



Wide variations were observed in the blood-diastase figure. The urine 

 diastase figures were low with one exception. All the cases, however, gave a 

 low diastatic concentration factor, as the above-mentioned exception (Case 41) 

 had a high blood-diastase figure. 



Urea Concentration and Diastatic Concentration Factor. 



In the cases shown in Table XI the urea concentration test was performed 

 and a comparison was made with the diastatic concentration factor. 



