I.\ 



is more than this; it is a laboral 

 in-lit of the chemist l>nt directed in the I 

 many activities by a guiding hand which 

 to man. Chemical transformations thai 



the greatest skill pro, 1 withoul appa ifficulty in I 



what are these changes due w I al is l 



gents and forces, and what is the dii 



in their varied activities) To these, which 



lions of genera] physiology, the reply n 



are the ferments or enzymes, and that the dii 



through the susceptibility of enzymic acti\ 



ronmenl in which the enzymes are acting. In mat 



can be explained on a physicochemical depei 



known laws of mass action or surfac lion; ii 



pend on purely chemical changes in 



in reaction or the accumulation of chemical sul 



poisons on the enzj me. Bui 1 1 ■ 



on influences which as yel arc quite unknown to tl • 



such as the changes in cell activity thai can be 



nerve impulse. 



These preliminary remarks will serve to indicate ti 

 which we musl firsl occupy our attention. Tl 

 chemical nature of saline solutions 

 ture of enzyme action. The knowledge which 



to be of value, not only 1 anse it will help 



of the workings of the normal healthy cell, bul 



it will indicate possible causes for derangemenl in cellul 



Buggesl rational means bj which we may 



THE PHYSICOCHEMICAL LAWS OF SOLUTION 



The 0«l La 



Three fundamental princip 

 for an understanding of the nati 

 we take a quantity of anj 

 called a '-Mam molecule or I 

 actly 22.4 liters at 

 that, as we compn 

 same proportion as the volume din 

 proportional to it- pn 



