Tin r.i OOD Mir. 



methylene blue or neut pal red, an <»t i 



in Borne '•'•lis in the form "i 



give :i reticulated appearance to the corpuscles I 



arc nunc abundanl in infants' blood and in pi 



vere anemia or hemolytic jaundice than in normal l>l<" 



taken as evideni E tin 1 youth <•!' tin- red '•••II ;i 



tive proci since the number of the reticulated 



in ihr blood is nunc or less directly prop 



activities <»t' the bone marrow, enumeration of the reticulated • 



of clinical importance in anemias. In conditions in whii 



been made plethoric by the transfusion of blood, it h 



the number '>t* reticulated cells is decreased; the bone ma: 



animals also shows ;i marked reduction in reticulated • 



The diminished rate of hi 1 cell formation Bometime 



transfusions may l"- explained by assuming that the Btimulus wl 



awakens the formation of red cells in the bone marro 



made subnormal on the injection of'red cells into the blood, an< 



the formation of red cells is depressed Small trai - 



fore preferable to large ones in cases in which tin- n 



linn is greatly impaired. By means of li\in>_ r cull 



r«>w the different Btages «'t' the development of th< 



true red corpuscles may be studied Towei and Herm Somi 



has been gathered from such Btudies which poii ts to 



in place of the red cells being cells which have l< r nuc 



the current teaching, they are rather cells which de 



bud and escape into the circulation as true red cells The nu 



red cell and the v>-<\ nucleated corpuscle of the bird are ti 



intranuclear activity and arc morphologically identical. 



Rates of Regeneration of Erythr. 



Microscopic examination of the hi 1 durii 



\>-i\ cells shows the presence of nucleated I 



in the blood have therefore been taken as an i 



blood regeneration. The evid upon which tl 



however, is hardly complete, Bince cl 



cell formation may be responsibli 



bone marrow is considered the 1 cell 



that an abnormal increase in the red bone 



increased red cell formation | 



about the new formation unnt 



max he an important ' 



large number of red cells in oondil 



