BLOOD CLO 1"1 



w ires. In this latter case, I clot d< 



manner, bnt the fine threads of fibrin 



ing behind the blood Berum with tin pp 



The fibrin removed in this way may then be 

 Berum. The -••nun and corpuscles now 

 is iisc<l for many physiological purposes Clottii 

 ated by allowing the blood to flov ovei exposed I 

 evidently added to it from the tissues whicl 

 process, this influence being particularly marked in tl 

 of the lower vertebrates Winn the blood 



eived through a cannula inserted directly into :i • 

 injury to the walls as possible, it very slowly cl< ill, bu1 



does bo it' the blood is allowed ti» come i 

 tissues, or if it is mixed with tissue extract eh a- I 

 Clotting is considerably accelerated by warming t ; 

 l>licntioii of a cloth or tampon well wrung out with 1 

 saline to a wounded Burface is a mosl efficient m< j I 



orrhage from vessels too small to ligi 



The Nature of the Clotting Process 



Plasma obtained by centrifuging hi 1 thai has bet 



clotting by one of the foreg - methods can be made to clol 



the inhibiting influence; for example, in i l«''l plasma by warm 



blood tn room temperature, in Baited plasma by dilul 

 an equal volume of water, and in decalcified plasma 1>\ addii 

 ••ii-nt amounl of soluble calcium Ball combine with all I 



oxalate and Leave a small trace of calcium Ball 



The first question coi rns thi 



it is furnished b) comparing the composition of I •••■■« 1 pi 



• if Berum. Though both of these fluids contain the pi 



and globulin, in approximately the same 



contains another protein not unlike globulin in most 



hut distinguished from typical globulin in tl 



half-saturation with sodium chloride, in which 



ble, and is more readil ' 



of the plasma with Bodium chloride, equal 



rated Bodium chloride solution arc n 



fibrinogen, as the Bubstancc is called 



the tube by centrifuging and is 



half saturated sodium ehlori< 



siihnl in weak saline solution 



bonate . will then be found to 



