can I"- extracted from the i 



belong i" the class of phosphatids, beii . if 



not identical w ith, kephalin II- ell). 



Intravascular Clottii. 



The practical applical ion of thi 

 manner in which 1 1 1 « - blood is maintained in a t!'ii«l 

 vessels, and the disturbance of tliis function ci 



ting. A< rding to the one theory, 1 1 1 « - blood is mar 



absence from it of anj considerable quantil 



to tin- other, by the presence in il of an amount of an1 ifli 



eienl to prevenl the union of calcium with protl 1 



is maintained even when large amounts of thrombin urn, 



which contains this substance, are injected int< We 



••an Iwsi explain the immunity <>t' the bl 1 to the action of thrombin 



der these circumstances ;^ being due to the i' n it 



of antithrombin in amounts sufficient to prevent the action of thr 

 on fibrinogen, for, as stated above, it is claimed b) Howell 

 thrombin lias this influence as well as that of p ting ti • 



of prothrombin into thrombin. 

 Intravascular clotting may be brought about bj 



1 Mechanical damage t" the lining of the 1»1 ! 



plication of a ligature, for example, the damaged < 



covered by a clot, which gradually becomes firmei 



spread up thr M^-rl t < . the next branch 2 l 



Bubstances in the blood. Emboli, for example 



to form at tin- places where thej stick, nam< 



Clotting is also a frequenl occurrence when tin 



tin- cardiovascular tube, ami it maj occur under imp 



conditions causing the condition known \ 



••stiiiL' variety of intravascular clottii 



nous injectioi ctracl - ll-rich 



lymph glands or testes Wooltlridg* Bj 



acid ami digestion with peptoi • 



extracts which, when dissolved in alkali 



u l.i r clotting effect 

 phorus, it is probable that th< 

 i nucleoalbumin Their action mi 

 thrombin, according to Elowell'a tl 

 bokinasi ding to M 



\- a matter of fact, h( 

 pletcly explained by either 1 I 



