i III tii vi;iiin \M> l-\l: \TH\ ROIP 01. • 



I .,., 



as myxedema, and here again the Bymptoms are very characteristic I 

 195). The skin is drj and thick, with a deposition of connective 

 often containing fal in its deeper layers; the hands and feet become 

 unshapely; the lips thick and the tongue somewhal enlarged, bo thai 

 when the person attempts to speak, it appears as if the tongue w< 

 large for the mouth ; the hair falls out ; there is a low bodj temperature, 

 and it can be shown that the energy metabolism is greatly depressed, and 

 thai a deficiency of oxygen is being consumed. It is said the person can 

 take a larger quantity of sugar than an ordinary individual withoul the 

 development of glycosuria, bu1 the depression of the metabolic function 

 causes the patienl to take sparingly of food, in spite of which, however, 

 the body weiehl maj steadily increase. The sexual function becomes 



./. B. 



Pig. l myxedema; B, ■ n montl ' I ■ 



depressed, and there is involvemenl of thi ous system wn by 



mental dullness and Lethargy. 



Although the thyroid gland is much atrophied in myxedema, sympto 

 thai are very similar may also occur when the gland is aously en- 



larged. As already explained, however, this enlargement is due merely 

 to an accumulation of colloidal material and is really an atrophic c< 

 dition. A patienl Buffering from endemic goiter may at fin ibit 



symptoms which are usually attributed to a hyp< etion of thyroid 



material into tin 1 blood (the Bymptoms will be described imm 

 Imt later these give placi ms not unliki I myxedema. 



It is concluded that the above conditions leficiei 



thyroid function, or hypothyt . beca ise I is atrophied, 



