BACILLUS OF SOFT CHANCRE 183 



BACILLUS OF SOFT CHANCRE 



Bacterium Ulceris Chancrosi (Ducrey). 



Streptobacillus of Soft Chancre. 



Morphology and Stains. A small thin bacterium .5;* broad, 

 1.5/1 long, growing in chains with polar staining, which can be 

 demonstrated in sections of chancroids without much difficulty. 



This organism does not stain by Gram's method, but by Lofflers 

 it is stained with ease. 



Cultures are hard to make. It grows best in serum agar, and 

 blood agar in faint colonies that are not very characteristic. In 

 condensation water of agar it grows feebly. 



In sections and in pus the organism is frequently found in the 

 interior of leucocytes. 



By aspirating pus from buboes and planting it on old but moist 

 blood agar plates, cultures may be obtained. 



Pathogenesis. From an old culture of over ten generations 

 typical ulcerations were produced in man. The organism is feeble 

 and quickly dies in culture media or in contact with mild 

 antiseptics. 



ANTHRAX BACILLUS 



Bacillus Anthracis. 



Anthrax Bacillus of Koch (Fig. 51). 



Practically the first pathogenic organism to be isolated. This 

 was accomplished by Dr. Robert Koch. It is the cause of a wide- 

 spread malignant disease, variously called Anthrax, Charbon, or 

 Splenic Fever. Animals and man are infected by it, and its action 

 is often rapidly fatal. 



Morphology and Stains. In animal tissues this organism ap- 

 pears as a large rod 3-10^ long, and 1-1.2;* wide. Is of ten in pairs 

 or chains. In fresh specimens the ends of the rods are rounded; 

 when older, the ends become square or concave. Often they have 

 faint capsule surrounding them. In culture media they exhibit 



