

BY DR. KLEIN. 51 



pale corpuscles and large granular ones, all exhibiting distinct 

 amoeboid movements. But the best place for observing these 

 bodies is the tail of the tadpole. If a portion of the tail is 

 taken from the thin menr^ranous part, and mounted in half 

 per cent, salt solution, migratory cells are to be found every- 

 where, consisting of finely granular protoplasm, and displaying 

 extremely active movements. 



With reference to the granular corpuscles it is not necessary 

 to add much to what has already been said. Among the best 

 examples are certain coarsely granular elements, which occur 

 in the intermuscular connective tissue of the frog. If the 

 transparent membrane which separates the muscles of the thigh 

 of the frog is spread out and examined in an indifferent liquid, 

 it is found that, besides active migratory cells, there are coarsely 

 granular elements possessing oblong nuclei of the most various 

 forms, which move very sluggishly. Perfectly similar bodies 

 occur in the sheaths of large nerves of the frog. Another 

 situation for studying these cells in great numbers is the tongue 

 of the same animal. A living frog having been secured in the 

 supine position, its mouth is opened and the tongue is drawn 

 out by its two cornua. Thin shreds are then snipped from the 

 substance of the organ (the epithelium having been first re- 

 moved in the same way) and covered in fresh serum. In a 

 preparation thus made, an immense number of large coarsely 

 granular cells appear, presenting the most grotesque forms. 

 (See Fig. 9.) 



Branched Cells (Connective Tissue Corpuscles). 

 Those bodies are fl.att.fned o.ejjft, consisting of finely g 



protoplasm: each contains a nucleus, which is also, for the 

 most part, flattened and oblong. They possess a greater or 

 less number of processes ; and by these, which are sometimes 

 branclTetTJ sometimes single, they are in continuity with each 

 other, so as to fflrm a network. In some connective tissues 

 the processes exhibit a more or less regular relation to the 

 body of the corpuscles ; in trthers, they are so short that the 

 corpuscles are almost in contact with each other, being sepa- 

 rated by scarcely any interstitial substance. In preparations 

 made in the way alreadj' recommended for the demonstration 

 of amoeboid cells of the subcutaneous connective tissue of the 

 rabbit, bodies are also found which are distinguished from thu 

 others by their very irregular placoid form, grenfcer size, and 

 hyaline appearuuee, as well as by the possession of oblong 

 nuclei. These cells contain very few granules, and those 

 mostly in the neighborhood of the nucleus. At first sight 

 these placoids seem to have only short projections, but, under 

 high powers, they are found to possess numerous long hyaline 

 radiating processes. 



