i8 



by Dr. Wilson White, showing the result of marriage of a nearly sound 

 stock in which the temperament was, generally speaking, of the sanguine 

 type; there was only one member insane at 55; she was unmarried; her 

 four sisters, who were all married, had some healthy, grown-up children. 

 The brother himself, perfectly sane and healthy, married a woman de- 

 scended from stocks in one of which there were many members suffering 

 with epilepsy (E.); indeed, her father and her grandfather suffered with it. 

 On the maternal side there was suicide (S.) of an aunt and insanity of a 

 grandfather; most of the members of this stock were of a melancholy, 

 brooding temperament. The result of the mating of these two neuropathic 

 stocks is shown. There were nine children, of which three, marked with 

 deep, black-rimmed circles, suffered with some form of neurosis, a male 

 congenital imbecile, a healthy male who has five healthy children, a child 

 who died in early life of convulsions, the patient's mother who became 

 insane at the age of 40, a female who became insane at the age of 20, 

 two females also suffered with some form of neurosis, lastly, a male who 

 died in early infancy. 



The next generation shows the result of mating this unsound stock 

 with an almost healthy, sound stock. There are not as many unsound 

 members as in the last generation, and we observe that the four members 

 that became insane at 19, 25, 30, and 20, all had their first attack at a 

 much earlier age than their mother, one of these committed suicide and 

 two were found dead ; this pedigree illustrates well the signal tendency to 

 the occurrence of antedating. The sound members of the stock apparently 

 inherited their temperament from the father's side, and the one member that 

 is married has quite healthy children ; this looks as if the unsound elements 

 of this degenerate stock had been cleared out by segregation of the unsound 

 germinal determinants, causing intensification of the disease and occurrence 

 of the onset at an early age, thus preventing propagation. 



Fig. 5. This pedigree shows the result of marriage of first cousins, in 



X 



Fig. 5 



