402 BOAKD OF AGRICULTUEE. [Jan. 



APPENDIX, 



TUBERCULOSIS. 



Tuberculosis undoubtedly prevails among the domesticated 

 animals over the entire globe, and has been well defined as a 

 universal panzootic. 



Its frequency depends upon various external influences, as 

 well as constitutional predispositions of different species and 

 breeds. The centres of this malady are met with in the 

 great centres of human population, and in these centres a 

 large per cent, of tuberculosis is found in mankind. 



This disease is of the greatest importance, since it has 

 been induced experimentally in animals of different species, 

 as carnivores, herbivores, and onmivores, by inoculation and 

 feeding for certain periods tuberculous material from the 

 lungs and glands of diseased subjects, as well as their milk. 



Since man derives a great deal, and in some instances 

 his entire sustenance, from the flesh and milk of animals 

 around him, we can scarcely doubt that an intimate casual 

 correlation exists between him and them with regard to the 

 disease. 



Tuberculosis has been demonstrated to be due to the bacilli 

 of tuberculosis by Koch, and that the germ will reproduce 

 itself innumerable times and retain its virulence. It will 

 not multiply outside of the animal body except by artificial 

 means, but it has been known to retain its activity in decay- 

 ing sputum for forty -three days, and in air-dried sputum for 

 186 days. Death has taken place from the inoculation of the 

 bacilli into susceptible animals as soon as ten days when 

 introduced directly into the circulation, in five or six weeks 

 when subcutaneously inoculated, and in from three to four 

 months when associated with infectious animals. These 



