44 POISONOUS PROTEINS 



frequent and violent. During a convulsion, oc- 

 casionally in an interval, respiration ceases. 

 The heart continues to beat, at first with no ac- 

 celeration and with perfect regularity. The ex- 

 act mode differs somewhat in different animals, 

 but is always that of anaphylactic shock. Ne- 

 cropsy shows the same conditions found after 

 death from anaphylactic shock. The peritonitis 

 found after death from inoculation or from the 

 injection of the unbroken cellular protein is 

 wholly wanting. 



When a nonfatal dose of the soluble poison is 

 administered, the symptoms are those described 

 above as characterizing the first and second 

 stages. There may be isolated and slight con- 

 vulsive seizures, but an animal seldom recovers 

 after the convulsions have become general and 

 frequent. With recovery the temperature slow- 

 ly rises and ultimately returns to normal. 

 Within two hours the animal is apparently quite 

 normal in every respect. 



