SERUM ANTISTREPTOCOCCICUM. ANTISTREPTICOCCIC SERUM. Dose 

 30 c.c. daily subcutaneously. 



The serum obtained from the blood of a horse immunised by repeated 

 injections of at first killed cultures of Streoptococcis pyogenes or S. ery- 

 sipelatus of many different stems, and later of virulent living culture. 



SERUM ANTIMENINGOCOCCICUM. A serum prepared in an analogous 

 manner by injections of the Diplococcus intracellularis, and used in the 

 treatment of Cerebro-spinal Meningitis. 



Theobromina. Theobromine. Dose, 5-10 grs.; 3-6 dgms. 

 A dimethylxanthin obtained from the seeds of Theobroma Cacao. A 

 white crystalline powder odourless with a bitter taste. Soluble 1 in 1,700 

 of water, 1 in 1,400 of alcohol. A compound with sodium and sodium 

 salicylate, Theobromine Sodio-salicylate, has a sweetish taste and is more 

 soluble, 1 in 1 of water, and is hence used in place of the alkaloid alone. 

 (It is sold under the trade name of Diuretin.) 



TERPINI HYDRAS. TERPIN HYDRATE. (Terpene Hydrate.) Dose, 

 3-10 grs.; 3-6 dgms. 



An alcoholic hydrate prepared from oil of turpentine. Colourless, glis- 

 tening crystals or a crystalline powder, with a slight aromatic odour and 

 a bitter taste. Soluble 1 in 280 of water, 1 in 14 of alcohol. 



Tuberculinum. Tuberculin. (Old.) Three months old gly- 

 cerine veal broth cultures of the Bacillus tuberculosis are concentrated 

 over a water-bath and filtered through a porcelain filter to remove the 

 bacilli. For treatment New Tuberculin or other similar preparations are 

 more largely used. 



TUBERCULINUM NOVUM. NEW TUBERCULIN. (Tuberculin 

 R.) The Bacillus tuberculosis is grown on glycerine-serum and the re- 

 sulting cultures scraped off and heated to 60 C. to kill the bacteria, dried 

 in vacuo and triturated. The resulting mass is emulsified and centrifuged, 

 the upper layer rejected and the lower again dried, triturated and again 

 emulsified and centrifuged, the upper layer is set aside and the residue 

 subjected to the same process. The resulting layers are preserved with 

 glycerine and standardised to contain 10 milligrammes of solids, in 1 c.c. 

 It may be used thus as a liquid or may be dried. The dose is calculated 

 as 1/6,000-1/1,000 mgms. of solid substance. 



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