482 THE PRACTICE OF VETERINARY MEDICINE. 



a rule there is heard a sh'ght cough about this time ; the 

 coat becomes dry and staring, and feels harsh under the 

 fingers ; the appetite becomes impaired to a slight extent, 

 and the animal gradually falls away in flesh. The nasal dis- 

 charge may in some cases have a watery appearance at first ; 

 soon there may be observed, if the case be closely watched, 

 the formation of little elevations on the Schneiderian mem- 

 brane, which in course of time become fully developed, 

 burst, and form ragged-edged and pretty deep ulcers, which 

 sometimes heal — such cases, however, being exceedingly 

 rare. When an ulcer of this description does heal, it leaves a 

 white cicatrice, very peculiar in appearance, and looking as 

 though incomplete. The Schneiderian membrane around the 

 ulcerated patches is of a pale or leaden colour. If the dis- 

 ease lasts a sufficient length of time, the Schneiderian mem- 

 brane becomes a mass of ulceration ; the ulcers run 

 together, or communicate, and are then described as con- 

 fluent ; the pituitary membrane may in many cases be 

 perforated; and the pulse is always found to be weakened, but 

 in many cases is not quickened, or if quickened, but very 

 slightly so. As the disease advances there may frequently 

 be observed a slight irritation of the eye on the same side 

 as the nostril that is discharging, and a slight purulent dis- 

 charge may issue from the affected eye ; this is frequently 

 one of the first symptoms to put in an appearance. On 

 making an examination the submaxillary lymphatic glands 

 are found to be hard and indurated, and pretty firmly at- 

 tached to the bone by the indurated efferent vessel ; in 

 some cases the ulcers may exist high up out of sight, and 

 no sign of ulceration be observed in connection with the 

 visible portions of the pituitary membrane. The discharge is 

 not offensive in odour unless the ulcers extend to and affect 

 the turbinated bones, in which case the discharge becomes 

 highly offensive in odour ; the ulcers may even extend to 



