GENERAL PATHOLOGY. ' 67 



before) the detacliment of the epithelium, and a more exube- 

 rant mass of such cells in the glands of the fourth stomach, 

 and small intestines, followed by the haemorrhagic erosions, 

 or so-called superficial ulcers. In the solitary glands of the 

 small intestines, in a less marked form than in the Peyer 

 glands, the cell development goes on, attended by the " so- 

 called plastic exudations and croupous deposits from the 

 follicles, the vesicular eruptions and the ulcers " of the glands 

 described by authors ; all owing their origin to the nature of 

 the cell changes. In the mucous glands of the membrane 

 lining the respiratory passages, there is cell multiplication, 

 associated with the extraordinary development of the ele- 

 ments of connective tissue, whereby the detached masses are 

 accounted for. The separation of these is the end of the 

 process, 



Brauell affirms that there are never and notvhere exudations 

 of lymjyJi. He also notices differential manifestations as 

 between the natural Einderpest and that from inoculation. 



"The nodules which appear on the skin owe their origin to the 

 modified development of the epidermic cells on small localized spots, 

 from which the deeper sooner or later become detached and result in 

 the dispersion of the nodules. The most superficial layer of the skin, 

 wherever it is covered by each nodule, sometimes suffers molecular 

 change." 



Perhaps the most important observation made by him in 

 inoculated cases, is that, in the lateral ventricles of the brain, 

 and particularly under the arachnoid over the cerebrum, 

 exudation is met with.* 



It may not be easy of comprehension how the imbibition of 

 the virus through the organs of the skin, should produce 

 such marked cerebral disturbances, not consequent upon its 

 inhalation by the lungs, or its absorption by the mucous 

 surfaces of the mouth, nose, &c. When this statement of 

 Dr. Brauell is connected with the general testimony of all 

 observers, that in a multitude of cases where the pest has 

 been induced by the seton or puncture, the lesions are more 

 extensive and serious ; it may lead us, as a teaching of practical 



 Kt ubi supra. (Cattle Plague, pp. 66-69.) 



