1917.1 PUBLIC DOCUMENT — No. 31. 89 a 



DEPARTMENT OF VETERINARY SCIENCE. 



JAMES B. PAIGE. 



In addition to the usual correspondence and diagnosis work 

 that has been carried on in the department during the past 

 year particular attention has been given to three lines of in- 

 vestigation and control work, as follows: — 



1. Prevention of hog cholera. 



2. Study of Bacterium pullorum infection. 



3. Suppression and eradication of bacillary white diarrhoea 

 in fowls. 



1. Prevention of Hog Cholera. 

 During the past year there has been at the disposal of the 

 department a herd of 75 to 150 hogs that have been fed upon 

 garbage, — from a source, in fact, that has on two previous 

 occasions furnished hog cholera infection to which two out- 

 breaks of considerable extent have been traced. To protect 

 the hogs in this herd from the infection brought to them in 

 this garbage and from other sources, anti-hog-cholera serum 

 and virus have been used extensively to produce a condition of 

 artificial immunity. During a part of the year the susceptible 

 members of the herd were treated by the simultaneous method, 

 the "Globulin" preparation of serum supplied by the H. K. 

 Mulford Company being used. The manifest advantage of the 

 "Globulin" over the usual anti-hog-cholera serum is dependent 

 upon its greater degree of concentration and its freedom from 

 organisms that frequently occasion serious complications when 

 injected subcutaneously or intramuscularly. For a part of the 

 animals a refined "Amber Serum" from the Mulford Company 

 has been employed, which, on account of its freedom from the 

 usual blood elements and its sterility, has been found to give 

 very satisfactory results. 



