254 GENERAL THERAPEUTICS FOR VETERINARIANS 



Curative Vaccination in Hog Cholera. — The serum inoculation 

 appears to have been proven to be also a curative method (see 

 p. 248). 



Curative Vaccination in Tuberculosis. — Tubercuhn, which was 

 recommended by Koch as a specific curative agent in tuberculosis 

 in man, did not prove to be effective for this purpose. Further- 

 more, it is of no value as a curative agent in tuberculosis of cattle. 



Curative Vaccination in Septicaemia. — Several sera are recom- 

 mended as curative and protective remedies in the diseases caused 

 by streptococci and for the complications of contagious pneumonia; 

 e.g., the anti-streptococcic serum of Marmorek and the sera against 

 purpura hemorrhagica of Lignieres and Jensen. The reports 

 concerning the action of these sera are contradictory. The Danish 

 polyvalent serum against purpura hemorrhagica (Jensen) proved 

 effective in a case treated by Frohner. 



Organotherapy. — The terms organotherapy, tissue-fluid therapy, and 

 opotherapy are used to designate the use of animal organs as curative agents. 

 Testicles, thyroid glands, ovaries, prostates, Uver, etc., as such, or in the form 

 of special preparations (spermin, thyroidin, iodothyrin, etc.), are used in 

 impotence (spermin), goitre and myxcedema (thyroidin, iodothyrin) and 

 diseases of the ovaries, prostates, Uver, etc., being administered internally. 

 Only the preparations of the thyroid gland in goitre and myxcEdema appear 

 to have an imdisputed action. Experiments in Germany with the other 

 opotherapeutic preparations have usually resulted negatively. 



III. Diagnostic Inoculation 



Purpose. — The object of diagnostic inoculation is to ascertain 

 experimentally the identity of the disease in cases in which a 

 certain demonstration and positive recognition of the infection is 

 not possible with the usual clinical methods. This is accomplished 

 by artificially inoculating healthy experimental animals with 

 infected masses (blood, nasal discharge, vaginal discharge, pus, 

 milk, faeces) in order to produce a typical picture of the disease 

 (inoculation of other animals), or by inoculating the originally- 

 diseased animal (self-vaccination, auto-inoculation). In a certain 



