GENERAL PATHOLOGY. 17 



pleura, and the two opposed patches of inflammation 

 may blend. This is the first stage in the formation of 

 adhesions, i.e., bands of connective-tissue between tlie two 

 surfaces. 



Lymph, similarly formed and composed of fibrine and 

 leucocytes, is the temporary uniting medium in healing by 

 the first intention. 



This form of inflammation may end in absorption. 



Productive Inflammation. — Often the inflammatory pro- 

 cess ends in the formation of new tissue, and is then termed 

 ' productive.' In these cases the fibrine disappears from the 

 exudation, and white cells crowd into it, converting it into a 

 tissue of closely packed white cells, in a scanty homogeneous 

 matrix, which is supplied by vascular loops springing from 

 the capillaries of the inflamed tissue, penetrating it in all 

 directions. This tissue is called granulation-tissue. The 

 granulations, when plentifully supplied with newly formed 

 vessels, gradually become converted into connective-tissue, 

 or scar-tissue. 



This tissue is at first very vascular. Gradually the new 

 tissue contracts, many of the vessels disappearing in conse- 

 quence, and eventually the scar-tissue becomes less vascular 

 than the surrounding parts. 



Granulation-tissue may, however, ' break down into pus,' 

 instead of forming scar-tissue. This is due to the insufiicient 

 development of vessels, diminution in their lumina, con- 

 tinuance of excessive irritation, and to the too dense packing 

 of cells. 



The term interstitial is applied to inflammations of solid 

 organs where the connective-tissue is chiefly involved. 



The terra parenchymatous is applied to inflammations 

 where the epithelial cells of the organs show the most marked 

 changes. 



Suppurative Inflammation. — Is a very common form. 



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