ATEOPIIY AND DEGENERATIONS OF TISSUE. 



65 



and tlie general characters of the affection, several organs beiag 

 simultaneously involved, point to some alteration in the com- 

 position of the blood as the cause of the change. In the instance 

 where I succeeded in tracing the nature of the deposit, the horse 

 had been lately bought, suffering at the time from what appeared 

 to the purchaser to be the remains of a cold, sore throat, or 

 strangles. "Wlien seen by me, five weeks after purchase, the 

 animal was much emaciated, and presented symptoms of disease 

 of the liver, and was evidently in a dying condition. The jpost 

 mortem revealed the liver much enlarged, weighing over twenty 

 pounds, and of a glistening, palish yellow colour throughout, 

 the new material being stained by the biliary matters; the 

 kidneys w^ere also enlarged, very solid, pale, and translucent 

 in appearance ; and when cut, tlie surfaces were smooth, blood- 

 less, and ghstening. The iodine test was most conclusive. It 

 is important to bear in mind that amyloid disease is essentially 

 chronic in its character, and when deposited to any extent, is a 

 sure sign that the animal has been in ill health for a period 

 extending over many weeks, or even months. 



b 



FATTY INFILTRATION. 



This essentially differs from fatty degeneration. In degenera- 

 tion, the fat is derived from a change of the protoplasm itself, 

 leading ultimately to the destruction 

 of the cells of the part. In infiltra- 

 tion, the fat is deposited between, as 

 well as within the cells, where it dis- 

 places and obscures the nuclei and 

 protoplasm, but does not destroy them. 

 In degeneration, the fat occurs in a 

 granular form within the cell contents. 

 In infiltration, the fat is deposited as 

 distinct drops, which may gradually 

 increase and coalesce, so that the cells, 

 ns in the figure, may be completely 

 filled and distended with it. The functions of the cells are but 

 little impaired by the accumulation, and are restored to tlieir 

 natural condition by the removal of the fat. 



Fig. 2.- 

 of heart, 

 intermixed 

 tissue. 



Fiifcty infiltration 

 Larije fat cells 

 with muscular 



