PLEURO-rNEUMONIA. 175 



was very severe, and complicated by gangrenous phenomena, 

 causing the death of sLx ; and lastly, the recoveries amounted 

 to 88-88 per cent. 



Following the method of Willens, Professor John Gamgee 

 introduced preventive inoculation into Edinburgh about 1857, 

 but the casualties were very numerous, many animals dying 

 from blood-poisoning induced by the operation; in fact the 

 operation was condemned as being worse than the disease. In 

 London it was condemned by Professor Simonds and others, and 

 to the present time it finds no favour there. 



Inoculation as reintroduced by Mr. Ptutherford, V.S., Edin- 

 burgh, has been attended with great success. 



Dr. Burdon Sanderson and other experimentalists recommend 

 the injection of the lymph into the venous system by means of a 

 small syringe, selecting the superficial aural vein for that purpose. 

 This method of inoculating, while inducing no local results, is 

 said to be quite as effective as that of inoculation of the tip of 

 the tail. 



Further investigations on the cultivation of virus, as recom- 

 mended by Pasteur with those of anthrax and fowl cholera, may 

 reveal the fact that an attenuated virus is quite as effective as 

 that removed from the pneumonic lung, and that successful 

 inoculation b}'' direct injection into a vein may be performed 

 without inducing any local ill effects. 



Intravenous injection has also been investigated by Professors 

 Thiernesse and Degive, who, having found that inoculation with 

 the lymph of pleuro-pneumonia in the cellular tissue of the 

 dewlap generally caused death, performed a series of experi- 

 ments, and concluded — 



1st. That the injection of pleuro-pneumonic virus info the 

 veins is not at all dangerous, if care is taken that not a single 

 drop of this liquid falls into the cellular tissue. 



2d. That this infusion possesses the same properties as caudal 

 inoculations, — that is to say, that it invests the animal body 

 with a real immunity. 



Professors Thiernesse and Degive inject the virus into the 

 jugular, and recommend certain precautions to prevent all con- 

 tact between the virulent fluid and the cellular tissue. If, 

 however, the steel cannula be plunged into a vein, and then 



