242 CONTAGIOUS DISEASES. 



secondary and by metastasis from the nasal membrane ; Phillippe 

 and Bouley being convinced by repeated post mortem examina- 

 tions that the primary lesions are always in the viscera, more 

 particularly the lungs, and that the formations in the nasal 

 membrane are invariably secondary. If, say they, a horse has 

 the 'jetage' (discharge from the nose), it is already thoroughly 

 glandered. It really matters very little which part of the body 

 is first affected. In either case the analogy with a tubercular 

 outbreak remains as strong as can be. The intestinal ulceration 

 of tuberculosis — in which we see the counterpart of the nasal 

 ulceration in glanders — is more often secondary to the pul- 

 monary disease, but occasionally shows itself before any evidence 

 of mischief can be detected in the lungs. Again, glandular 

 enlargement of a severe and persistent kind constitutes an im- 

 portant part of glanders, as it does of tubercle. The mode of 

 invasion is likewise identical in the two diseases ; now acute, 

 foudroyant, destroying life in a few days as by an overwhelming 

 blood poison ; now chronic, so as to last for years. Further, in 

 the chronic form, the same recurrence of acute attacks compli- 

 cating and adding to the chronic mischief is observed in glanders 

 as in tuberculosis. To read a description of chronic glanders is, 

 mutatis miitandis, to read an account of chronic phthisis. It is, 

 therefore, not surprising that Dupuy goes so far as to say that 

 glanders is a tubercular disease in the horse. In speaking of 

 the supposed causes of tubercle, we purpose presently to follow 

 out still further this remarkable tln^ead of resemblance ; but for 

 the present it will suftice to say that glanders is transmissible 

 by inoculation, and contagious from horse to horse, and that it 

 is also unmistakeably communicable from horse to man. Can 

 we hesitate to believe, says Villemin, that the parallel between 

 tubercle and glanders must hear find its completion ? To con- 

 clude, glanders and tubercle are so closely akin that they must 

 be looked upon as nearly related species of the same genus." — 

 (Braithwaite's Retrospect of Medicine, vol. Iviii.) 



Whilst admitting the close resemblance between glanders and 

 tuberculosis, and of the similarity of the microbes found in both 

 diseases, we must hesitate to admit their identity, for the broad 

 fact remains that inoculation with glanders produces glanders, 

 whilst inoculation with tubercle is followed by the development 

 of tubercular nodules. 



