IXODIC ANi^MIA — TEXAS FEVEK, ETC, 435 



tween the red cells. They were much more numerous 

 in the blood exuding from the cut organs, especially the 

 liver, spleen, and, above all, the kidney. They stained 

 more deeply than the former by Loeffler's method, but 

 were decolorised completely by Gram's method. 

 (3) Faint bodies, in some foci of a pale brick-red tinge, 

 never observed within but only between the cells. 



The purposes of our inquiry are sufficiently served 

 by the fact that the bodies I have observed are 

 identical in essential respects with some of the forms 

 described as being found in the blood by those who 

 studied that fluid in the disease known as Texas fever. 



Any slight differences which may exist between what 

 I and others have seen are only to he expected in 

 view of the modifications which the disease must neces- 

 sarily exhibit under such various conditions in different 

 countries. The study of this condition is yet in its 

 infancy, and one has only to think of the very striking 

 homology between this disease and malarial fever in 

 man, to realise how many differences must necessarily 

 be found in so many forms of the same disease. 

 The minute examination of organs not apparently abnormal 

 to the naked eye shows the following : — 



(1) The liver :— 



(«) The liver cells were, in some cases, the more acute in 

 a state of cloudy swelling, their nuclei being almost 

 all obscured. A fatty degeneration of the cells was 

 presented in the more chronic cases, and in many a 

 slight amount of abnormal pigment appeared within 

 the cells. 



(h) The bile capillaries in two cases were full of a dark 

 yellow pigment, appearing as beautiful radii from 

 the central vein of the hepatic lobule. 



(c) The blood capillaries were visible only here and there, 

 and did not present any abnormality either in their 

 walls or contents. I have not yet observed any abnor- 

 mal contents in the capillary blood of the organs. 



(2) The chief abnormality in the spleen was the presence 



of an unusual number of masses of granular sienna- 

 coloured pigment witliin the large cells of the splenic 

 pulp and the endothelioid cells of the stroma. Also a 



