SUPPURATION. 



33 



surface whose continuity is perfect, as from one in which there 

 is a breach. In every case granulations arise out of tlie tissue, 

 and it is not essential there should be loss of substance ; they 

 are found upon bone without any loss of substance having pre- 

 ceded them. They are found also in direct contact with the 

 cutis under intact epidermis, and Avith mucous membranes ; and 

 only in proportion as they become developed do the mucous 

 membranes lose their normal character. 



Well-formed, perfectly ela- «- A, S 



borated, healthy pus is a smooth, (^ 



rather greasy, sometimes viscid, z^^/^:^ 



yellowish-white, or cream-col- ^B ^pl 



om-ed substance, of a higher "■ <>, 



specific gravity than water, aver- 

 aging generally about 1-030 

 having little or no smell, and of 

 an alkaline reaction. Microsco- 

 pically it is found to consist of 

 certain essential constituents, 

 namely, pus corpuscles ; which 

 measure about 2-5 Vtj ^o 31515 t) 

 of an inch in diameter, are pel- 

 lucid, filled with semi-fluid 

 albuminous contents, and some- 

 times containing a few minute 

 oil globules. Along with the 0^ tr' qc 

 pus cells floating in the clear 

 liquor puris are often seen 

 minute clear particles, which 

 seem to have some relation, as 

 nuclei or rudiments of the cells. 

 These minute particles are not 

 more than i o-,Vo-d o^ ^^^ inch in 

 size. These two solid consti- 

 tuents float in a fluid or serum, 

 called the liquor puris, and the 

 shape of the cells depends on 



Fig. 7.— Cells from fresh catarrhal 

 sputa. A. Pus corpuscles, a. Quite fresh. 

 h. When treated with acetic acid. Within 

 the membrane the contents have cleared 

 up, and three little nuclei are seen. 

 B. Mucus corpuscles, a. A simple one. 

 b. Containing pigment graniUes. 300 

 diameters. —(ViRCHOW. ) 



@ 



"-ft c 



o 



!FlG. 8. — ^. Pus corpuscles, a. Fresh. 

 h. After the addition of a little water. 

 c-c. After treatment with acetic acid, 

 the contents cleared up, the nuclei 

 which were in process of division, or 

 already divided, visible at e, with a slight 

 depression on their surface. B. Nuclei 

 of pus corpuscles, a. Simple nucleus 

 witii nucleoli, h. Incipient division, with 

 depressions* on the surface of the nuclei. 

 c. Progressive bi-partition. d. Tri-par- 

 tition. C. Pus corpuscles in their natu- 

 ral position with regard to one another. 

 500 diameters. —(ViRCHOW.) 



* By many held to be nucleoli. 



Sometimes a distinct, circular, 



the density of this liquor puris. 

 dark-edged nucleus may be seen in the paler corpuscles, and 

 sometimes two or even three particles, like a divided nucleus. 

 D 



