42 TERMINATIONS OF INFLAMMATION. 



The second result is attained by the observation of what 

 happens when, instead of first cauterizing tlie eye which is 

 destined to be the recipient of the transplanted cornea, it 

 is left uninjured. At the end of twenty-four hours the cor- 

 puscles of the transplanted cornea are found quite unaltered, 

 and so distinct that the plan is strongly recommended as a 

 method of demonstrating their normal character. — (Klein, 

 Sanderson.) 



These varied results seem therefore to show, beyond the pos- 

 sibility of dispute, that the structural changes in the cornea of 

 the frog cannot be dependent either upon any influence ex- 

 ercised by the nervous system, or by transmission of the irrita- 

 tive effects from one structural element to another, so that we 

 have good ground for concluding with Professor Strieker that 

 they result exclusively from the stimulating influence of the 

 exuded liquid. The precise physical or chemical conditions are 

 as yet unknown, and are at the present moment subjects of further 

 investigation. Whilst these experiments prove that the forma- 

 tion of pus is sometimes due to the power of the white corpuscles 

 of penetrating living tissue, they do not destroy the facts that 

 the formation of pus may be independent of their presence. In 

 the case of pus formation in cartilage — where the cartilage cells 

 are isolated in cavities in the matrix, having no communication 

 with each other, but entirely closed — it is seen when the surface 

 of the cartilage is irritated, that the cells in the neighbourhood 

 of the irritation enlarge, and expand their capsules. The pro- 

 toplasm of which each cell consists becomes more granular, and 

 soon contains two corpuscles in its interior instead of one, and 

 has a gathering of protoplasmic matter around itself. This 

 process of division is repeated in each segment until every 

 cavity contains a mass of nucleated cells, which at length as- 

 sume characters corresponding with those of newly formed pus 

 corpuscles, while at the same time the original interstitial sub- 

 stance gradually wastes away and is finally represented by a 

 sponge-like stroma, in the holes of which groups of young cells 

 are contained. 



In this process we have a typical example of germination ; 

 the permanent ceUs which have for their function the main- 

 tenance of the unchanging life of the tissue, are replaced by a 

 more numerous progeny of transitory mobile ceUs, which live 



