140 



XFW" VnKK Z<^()L()GICAL SOCII-.TN' 



PLATE II. CASE NUMBER 6.— THORAX AND SPINAL COLUMN OF 

 MONKEY SHOWN ON PAGE 131, EXHIBITING DEFORMITIES. 



this early stage of the disease, it will be found that there are 

 marked changes going on, especially in the bones. 



Considerable alteration in the form of the thorax will be found. 

 The resistance of the bones is greatly diminished, and they break 

 under a slight strain, so that fractures (particularly green stick 

 fractures) and distortions are apt to be met with. Marked 

 osseous changes may take place, apparently without constitutional 

 symptoms. However, the ])aticnt soon loses its sjjirit and tlie 

 general health fails. 



The skin i> drv and the hair lustreless. There is beginning 

 emaciation, the muscles l)ecoming soft and flabby. The animal 

 is generally subject to fref|uent attacks of indigestion, accom- 

 |)anied by swelling and abdominal ])ain. .Vo urinary manifcsia- 

 lions are present in this stage of the disease. 



Partial paralvsis of the ])ostcrior extremities soon comes on, 

 with atrophy of the muscles of the loin and limbs. The progress 

 of the disease is now generally quite rapifl. anrl the aniuial lies 

 huddk-d up in a corner of its cage; if furcid to move, rises 

 languidly and with difficulty, and moves the limbs rigidly, as if 

 thcv were without joints. Its locomotion is extremely cumber- 



