Ui-J NEW YORK ZOOLOGICAL SOCIETY. 



of cartilage cells, w hile the centers arc made up of diffuse hyaline 

 tissue containino^ only occasional cells, a few fibers and an occa- 

 sional spicule of incompletely calcified tissue (plate 6, Fig. A). 

 Manv of the cartilage cells in these areas show karyokinetic fig- 

 ures and cell division is evidently actively taking place. The 

 spaces of the cancellous portion of the bone are for the greater 

 part completely occupied by mucoid tissue, in places containing 

 few cells mostlv resembling embryonic connective tissue cells, with 

 a few scattering leucocytes and plasma cells ( plate 6, Fig. B). In 

 other ])laces the homogenous matrix of mucoid tissue is densely 

 infiltrated with cells of man.\' t\i)es. ])olynuclear leucocytes, many 

 of which are cosino])hiles, normo])lasts, megaloblasts, osteoclasts, 

 of particularly large size, and small round cells with occasional 

 plasma cells. These cellular areas are ])articularly frequent about 

 the walls of the blood vessels. X'ewly formed blood vessels are 

 fre(|uent. Pigmentation, as from broken-down red blood cells, 

 is found in a few areas where ap])arently small extravasations 

 from the new vessels has taken place. 



In tile ])re])aration of this bone for microscopic examination but 

 sliglit decalcification was necessary, and before this was begun 

 the bone could be easilv compressed between the fingers. 



Cask ix. 



Diana Monkey (Ccro/^ithccus diana). — In this case the paral- 

 vsis of the posterior extremities was earl\- mani tested, .\nimal 

 continued to take its food well up to within day of death. Super- 

 ficial ulcerations developed on several parts of hind limbs. Ema- 

 ciatif)n or atrophy not excessive in this case. 



rOST-MORTEM SUMMARV. 



Body. — Moderately emaciated. Heart. — Systole, normal. 

 Lungs. — Bronchitis. Lk'cy. — Congested. Kidneys. — Congested. 

 Spleen and Lymph Xodes. — .\naemic. Stomach and Intestines. — 

 Contained considerable ])artially digested food ; mucous mem- 

 branes anaemic. (ienifo-Crinary Tract. — Negative. Osseous 

 System. — Marked changes in all tlie bones. .Soft and easily 

 brr)ken. Thorax and ])elvis greatly distorted. \'ertebrae easily 

 cut. 



Monhrancs. — llotli tlie dura inatt'r ;ind tlie pia are lliielsent-<l 

 throughout their entire course, the thickening bi'ing in .idnli con- 



