164 ^'l•-\V VORK ZOOLOGICAL SOCIETY. 



osteoclasts coulil l)c dcinonstrati'd and the osteogenitic layer of 

 the ])eriostiuni cannot be clearl\- ditTerentiated. 



The com])act ])orlions of the hone are made up of a frail net- 

 work of thin i)lates and spicules, and in many of these narrow 

 septs the Haversian canal is occu]Med jjy tissue similar to that to 

 be described as occuj^yinc^ the cancellous crypts. These spaces 

 are filled, to the exclusion of fat, by a dense mass of cells, the 

 intei;"ers of which are for the g'reater ])art mononuclear cells re- 

 seml)lin^- lymphocytes; with these are associated ])ol\'nuclear leu- 

 cocytes, amon_g- which eosinophiles are very common: red 1)lood 

 cells, largely nucleated : ])]asma cells and large ])olymor])hous cells 

 which have long slender ])rocesses that ap]mrentl\- make up the 

 chief framework of the tissue. The endostium is entirely want- 

 ing- in many i)laces ; in a few others it is represented by a nearly 

 normal, though highlv cellular membrane, but. as a rule, the cal- 

 careous tissue changes directh' into the marrow ]n\\p or to a layer 

 of larg'e cubical, or ])ol\gdnal, cells. auKing which are rn.'(|uent 

 larger polynuclear osteoclasts (plate 5, i'^ig. Ai. Thin walled 

 blood vessels are very numerous in the cellular i)uli). and blood 

 cells, both nucleated .and nonnucleated. are scattered throughout. 

 In a good manv areas masses of brown ])igment are found, evi- 

 dentlv resulting from the breaking down of blood, (liant cells 

 are \x'ry numerous throughout this ]n\\\) and the cytojilasm of 

 some of them a])pear to contain calcareous granules. The gen- 

 eral a])])earance of this pulp, the stoma of which is very scant, 

 resembles almost identicallv a <jiant celled sarcoma. 



Case x. 



Macaque ( Macaciis cxiioinols^iis). — This was a mildlv ])rogress- 

 ing case of "cage ])aralysis,'' extending over a period of one vcar. 

 Only at the late stage of the disease were emaciation and atro])liy 

 of hind limbs marked features. 



i'0.sT-MoR'n:.M .sr.M .\l.\K^■. 



Body. — Shows marked atrophy; cur\ature of s])ine. Heart. — 

 Diastole, normal. Lidv^s. — I'igmented ; otherwise normal. Liver. 

 — Congested. Kidneys. — Congested. Sf^leeii and Lynif'/i Xodes. 

 — Congested. Stomach and Intestines. — Anaemic. Genito- 

 urinary Tract. — Negative. Osseous S\ste))i. — .Ml bones show 

 general softening. Thorax laterally C(>mi)rcs^i'd. Ribs almost en- 



