74 CULTIVATED VEGETABLES. 



and quiet, that no happiness in the world can 

 surpass the charms of this agreeable ecstasy." 

 But if the dose be immoderate, or excessive, 

 and the impression exceeds the bounds pre- 

 scribed by nature, as in drunkenness, these 

 transports of joy degenerate into ridiculous 

 mirth, deliriousness, &c. or end in profound 

 sleep and lethargy ; or a palsy, apoplexy, or 

 sudden death, finish the tragedy, according 

 to circumstances. 



Willis* observes, that some, by taking a 

 small pill of laudanum, have been thrown 

 into so profound a sleep, that they could 

 never afterwards be roused out of it ; and 

 though from their pulse, respiration, and 

 heat, they seemed to be alive, and in a 

 due state, for three or four days, yet they 

 could never, either by internal remedies, or 

 external applications, be recalled to sensa- 

 tion and waking. The same author tells 

 us, that he has known a small dose of opium 

 take so contrary an effect upon other consti- 

 tutions, that they could hardly sleep at all, 

 but that they immediately became worse 

 with respect to their pulse, respiration, and 

 heat; they became more breathless, and could 



# Pharmacop. Ration. Part i. 



