CONTAGION. 221 



not often we hear of inoculation being practised in the horse. I 

 performed it once myself on a healthy middle-aged horse : whether 

 the result proved glanders or not my reader shall determine. 



On the 11th of September, 1818, I inoculated a brown horse, 

 then about seven years of age, upon the septum nasi, with matter 

 of glanders procured from the slaughterer's at Cow Cross. On 

 the third day there was a pimply and slightly tumid condition of the 

 part of the membrane inoculated, accompanied by some trifling 

 yellow albuminous issue from the nostril, and swelling of the sub- 

 maxillary lymphatic gland of the same side ; and on the fourth 

 day there was evident ulceration, with augmented discharge, and 

 that of a purulent character. On the fifth day there were to be 

 plainly seen two large unhealthy-looking ulcers upon the inferior part 

 of the septum nasi, and there was a mixture of pus and mucus ejected 

 from, as well as adhering about, the external nostril ; and from the 

 enlarged submaxillary glands was proceeding along the hollow 

 between the jaw-bones a cord of tumefied absorbents of the size 

 of my wrist. On the eighth day the ulceration had become deep 

 and extensive. On the eleventh, another cord of absorbents pro- 

 ceeded from the swollen submaxillary glands, over the side of the 

 face, to the affected nostril; and next day suppuration had taken 

 place in a couple of buds upon the cords of absorbents. On the 

 fourth day after inoculation, barytes, in its pure or caustic form, 

 was administered, a medicine in which, at that time, my father and 

 myself placed great faith as a remedy for glanders ; and the same 

 medicine was prescribed throughout the case. From the twelfth 

 to the twenty-ninth day no material change was noted ; but, on the 

 thirtieth day, such were the alterations for the better that hopes, 

 which had almost been abandoned, suddenly and unexpectedly 

 were revived, and there seemed every prospect of recovery. The 

 ulcerations upon the septum were manifestly healing, all swelling 

 had left the nostril, and the enlarged glands were diminishing. 

 On the thirty-seventh day there remained but the cicatrices of the 

 ulcers to be seen, with some slight mucous discharge. The ap- 

 pearances of farcy were vanishing also ; the farcy-buds, or rather 

 ulcers, healing and cicatrizing ; but the enlarged gland under the 

 throat felt soft and disposed to suppurate and ripen. By the 



