'2±2 CAUSES 01' CLANDERS. 



fiftietli da}', however, all signs of disease had disappeared save 

 some trifling remains of induration underneath the jaw. 



If this was not a case of glanders and farcy, it was, at all events, 

 a case that nobody, save through the test of inoculation, could, for 

 the most part of its progress, have distinguished from glanders and 

 farcy ; and that it was not I can imagine many veterinarians will 

 contend, and for two reasons ; — one being, that the enlarged sub- 

 maxillary gland shewed a tendency to suppurate, though, after all, 

 it did not break ; the other, that the case ended in recovery. It 

 must be remembered, however, that other instances of alleged 

 '' cure" stand on well-authenticated record ; and that, therefore, this 

 might have been a case, like many or most of them, of spontaneous 

 recovery, and consequently there was no absolute need of ascribing 

 the horse's getting well to the barytes. 



May 24:th, 1820, I inoculated an ass about ten or twelve months old with 

 matter taken from a horse of Mr. Stowe's, a farmer, at Farnborough, suspected 

 to have (chronic) glanders. No effect followed. On the 28th I repeated the 

 inoculation with matter taken from the frontal sinus of Lieut. Rich's horse, 

 also suspected of having (chronic) glanders. June 6th, still no appear- 

 ance of disease. I next procured some matter from an acutely glandered 

 subject, standing for slaughter at Cow^ Cross, and with it repeated the inocula- 

 tion for the third time, as before, scarifying the o2a iias/\ and rubbing the 

 virus upon it. On the fourth day after this last inoculation the nostril had 

 become swollen and tender, and had a knotty feel, evidently from lymphatic 

 inflammation ; the submaxillary gland of the same side was also swollen and 

 tender on pressure. On the sixth day a foul ulcer appeared upon the inocu- 

 lated part. On the eighth there came discharge from both nostrils ; and the 

 ass had fallen very lame in the near fore leg, seemingly from an attack (as 

 yet concealed) of farcy. Ninth dai/, the animal commenced heaving at the 

 flanks, and appeared altogether very ill, continually lying down, &c. Three 

 pintsof blood were drawn ; this, however, was no sooner done than he became 

 faint from its loss, and staggered, and died about five minutes afterwards. 

 Examination of the head shewed the Schneiderian membrane, on both sides, 

 reddened and thickened in substance, its surface studded with small white 

 tubercles, which, in a short time, would have turned to ulcerations; likewise 

 the nasal meatus were filled with sero-mucous discharges. 



No question, I should imagine, can arise, that, in the case of the 

 ass just related, glanders and farcy also were produced by inocula- 

 tion. The same fact stands likewise proved in the case extracted 



