SEAT AND NATURE OF GLANDERS. 255 



" In like manner lie (Lafosse) constantly observed an agreement 

 between tlie ohsiruction of the sublingual glands, or glands under 

 the jaws, and the affection of the aforesaid membrane ; that is to 

 say, if one of these glands only was obstructed, then the horse dis- 

 charged matter only by one of his nostrils ; but, on the contrary, 

 if both the glands were affected, matter should be discharged from 

 both nostrils." — '' One may (therefore) reasonably conclude with 

 M. Lafosse, remarks the Academicians, *' that the glanders does not 

 depend upon a general distemper ature of the blood, but is really 

 and truly A SIMPLE AND LOCAL MALADY." 



In 1752, Lafosse presented the Royal Academy with " A '^(iw 

 Memoir," " improving and bringing to perfection his discovery." 

 Herein " he distinguishes seven kinds of discharges which may 

 come from the nostrils of horses." — " He, also, makes it evident that 

 the true glanders has its characteristics, which essentially distin- 

 guish it from every other disease that has been called by the same 

 name." — " And, in order to prove that a great inflammation of the 

 pituitary membrane is always the cause of glanders, he has at- 

 tempted to bring on an inflammation upon the same membrane by 

 a corrosive injection ; and, when the injection was only made on 

 one side, the maxillary lymphatic glands were swelled on the same 

 side, and that nostril only produced the discharge. But, on the 

 other hand, when both nostrils were injected, these symptoms ap- 

 peared on both sides." — " The first Memoir presented by Sieur 

 Lafosse was confined to a bare description of the disease, and only 

 a proposal of a method of cure by way of project ; but, in this, he 

 certifies that he has cured several glandered horses by means of 

 his injections and fumigations thrown into the nostrils*." 



LAFOSSE, JUNIOR, 1775, strongly advocating his father's doc- 

 trines, contended that the most conclusive and satisfactory evidence 

 of their truth was afforded by repeated autopsies, and by the well- 

 known experiment so often made by his father, as well as by him- 

 self, of throwing corrosive injections upon the pituitary membranes 

 of horses, and of so turning them glandered. He shaped his father's 



* Observations and Discoveries made upon Horses, &c. By Sicur La Fosse, 

 Farrier to the King of France, 1755. 

 VOL. III. L 1 



