SEAT AND NATURE OF GLANDERS. 267 



ing Coleman, he reckons but '* two species of glanders, — acute and 

 chronic^ — "The acute disease is situated in the nasal sinuses, 

 and is frequently a primary disease, as well as a sequel of other 

 diseases previously existing in the system, particularly farcy, 

 which has probably occasioned them to have been mistaken for the 

 same disorder. But, notwithstanding they are produced by the 

 same cause, and appear in the same subject, they are nevertheless 

 distinct diseases, having no other affinity than there is between a 

 primary and a secondary disease." Mr. Smith has '' seen glanders 

 without farcy produced by diseased liver" — and " both farcy and 

 glanders are the consequence of diseased mesentery" — also farcy 

 by itselfand glanders by itself from the same. — '' When glanders is 

 a concomitant of farcy, it is generally in consequence of that disease 

 having extended to the mesentery;" — this membrane "falls into 

 decay, and then glanders appears, generally, a few days before 

 death ; not because it is the same disease, but because the nostrils, 

 being an extreme part, and their living power diminished, the 

 mucous membrane becomes susceptible of inflammation, which is 

 probably excited and increased by the ingress and egress of the 

 air in respiration :" &c. Mr. Smith has " never seen death oc- 

 casioned by the acute glanders, except by suffocation or hcemor- 

 rhage. If it was a constitutional disease, would it not affect the 

 system, and produce death in a variety of other shapes ? In the 

 chronic state, glanders does not produce any other disease in the 

 system" — " nor occasion death, except by destroying the orbitary 

 processes of the os frontis, and affecting the brain.'' In one sub- 

 ject he has " seen death occasioned by a morbid affection of the 

 brain." In another, " matter compressing that organ so as to 

 occasion lethargy." 



Aygalenq, a French physician, in a pamphlet, published in 

 1809, entitled, " Aper9u General'sur la Perfectibilito de la Me- 

 decine Veterinaire," in proposing to adopt names derived from 

 human medicine for our veterinary ones in ordinary use, suggested 

 for glanders that of " affection contagieuse du systeme lym- 

 phatique ;" plainly shewing from this what his views were in 

 regard to the pathology of glanders. 



DUPUY, 1817, whose celebrated work on TUBERCULOUS 



