272 SEAT AND NATURE OF GLANDERS. 



that any amelioration that took place of the patient under its 

 influence was attended by a correspondent diminution of the 

 quantity of albumen. In some horses virulently glandered, albumen 

 constituted seven-eighths of the mass of blood. And this excess of 

 albumen in the blood, Benard ascribes rather to disease of those 

 excretories of the body which give issue to albuminous secretions, 

 than to irritation or modification of the vitality of organs whose 

 function it is to renovate the circulating fluid*. 



Barthelemy, in discussion before the Royal Academy of 

 Medicine, Avished to be understood that he had never pronounced 

 glanders to be a local disease. Acute glanders cannot be con- 

 sidered as a local affection, from the circumstance of its being 

 accompanied by an eruption all over the body : it is a constitu- 

 tional malady, whose principal, essential, characteristic effects 

 shew themselves in the nasal cavities. Nevertheless, some facts 

 lead him to believe that the particular affection, denominated chro- 

 nic glanders, is a local disease*. 



Delafond thinks that glanders is often bred in the system. 

 So far from imagining that the disease originates ahvays in the 

 pituitary membrane, he affirms that in an immense majority of 

 cases its seat is in the lymphatic system ; and that its nature con- 

 sists in an alteration, about which we know little, of the lymph as 

 well as of the vessels conveying it*. 



HURTREL D'Arboval sums up the ancient as well as modern 

 doctrines on glanders, and concludes his interesting summary with 

 his own notions on the subject : — *' Lafosse appears to us to have 

 been the first to have hit upon the true seat of glanders. In shew- 

 ing glanders to be a local malady, confined to the cavities of the 

 nose, to the sinuses connected with it, and to other parts of the 

 nasal membrane, he has established a fact which to us appears in- 

 disputable, one that is actually admitted — as, indeed, it ought to 

 be — by all candid persons, by all such as make it their rule to 

 found their medical observations upon pathological anatomy and 

 physiology." — " If we have been thus fortunate in our discovery 

 of the true seat of glanders, it only remains for us to agree concern- 



* D'Aiboval's Dictionary, article " morve." 



