SEAT AND NATURE OF GLANDERS. 275 



become discharged through the nose, and thus constitute glanders. 

 hi the early stage, even in this (tuberculous) condition of lung, 

 Professor Sewell believes that many horses are recoverable. He 

 has ascertained that matter taken from these suppurated tubercles 

 (vomiccB) will by inoculation produce glanders as surely as one 

 (planted) potatoe will produce another. Asses inoculated with 

 such matter have had tubercles produced in their lungs in the 

 space of five days ; and what renders this experiment more satis- 

 factory, is, the fact of asses rarely having (from other causes) 

 tubercles in their lungs. 



YOUATT regards glanders as " inflammation of the Schneiderian 

 membrane, strictly local for awhile, and during its insidious state; 

 and even when the discharge becomes gluey, and some time after 

 chancres have appeared, the horse is apparently well." — *' I can- 

 not say," continues Mr. Youatt, " that glanders, like the rot, im- 

 proves the condition; but I have seen that often, and for a long 

 while, for months and even for years — it does no injury to the 

 general health. The inflammation is purely local, and is only 

 recognized by that invariable accompaniment of inflammation, — in- 

 creased secretion. Although that secretion is poisonous, and its 

 neighbours fall victims to it, it affects not the animal whence it 

 came. But this continued inflammation at length tells, or other 

 circumstances increase its power and its effect, and the vitality of 

 the tissue is destroyed and suppuration succeeds; but not that of a 

 healthy character — not that which is connected with reproduction ; 

 — it is malignant and destructive from the beginning ; and soon 

 another process commences, salutary or destructive, according to 

 circumstances. There are absorbents on every surface ; they are 

 found on the surface of the chancres which are beginning to appear ; 

 and they take up the fluid which is secreted from the ulcers, and 

 they soon feel its poisonous influence. The absorbents become in- 

 flamed and tumid, and, where the virus rests, as it were, viz. at 

 the valves, destruction of the part ensues, and the chancres spread 

 in every direction." — " Some portion of the venom passes on, and 

 is carried into the circulation and mixes with the blood, and vitiates 

 the blood." — " Then comes the constitutional affection. The mem- 

 branes of the neighbourhood, and those most susceptible of irrita- 



