NATURE OF GLANDERS. 289 



tioii result pale ulcerations, reddish at their bases, and more or less 

 deep in proportion to the magnitude of the pimples. Their uneven 

 borders, like those of the pimples, are indented, the ulcerations re- 

 sembling leaves that have been eaten by insects. On occasions, 

 indeed, they present the true worm-eaten aspect (vermouhcres*) : 

 their edges, however, continuing rather prominent so long as any 

 thickening remains. These ulcerations, no more than those super- 

 vening on farcy-buds, shew no disposition to cicatrize : commonly 

 they spread, and never cicatrize at allt. When very deep, and 

 they take to closing, they do so through forming indurated promi- 

 nent cicatrices, in substance white, corrugated, and radiated |." 



" The pimples or tubercles, or tuberculous risings upon the mu- 

 cous membrane of the nose, form with more or less celerity, remain- 

 ing a longer or shorter time in the state of pimple. Their progress 

 is quicker than is commonly believed : I know for certain that from 

 four to six days, at most, suffice for some of them to commence in 

 pimple and terminate in ulcer." 



" The excoriations and superficial ulcerations of the nasal mem- 

 brane in glanders take their rise in the same manner as the deeper 

 ulcerations we denominate chancres. And similar lesions are to be 

 observed upon the mucous membrane of the larynx, the Eustachian 

 tubes, the trachea, and the velum palati. The cartilages of the 

 nose, larj'nx, and trachea, become likewise, on occasions, the seats 

 of tubercles and ulcers." 



" There are other lesions of the Schneiderian membrane which 

 still bear the strongest analogy to certain forms of farcy. These 

 consist of pimples, more prominent than the preceding, rounded, 

 solitary or confluent, and either red at their origin, or else white, 

 surrounded by a circle of red. At first they are hard, but they 

 soon grow soft and turn to ulcerations, which spread with rapidity. 

 Their especial seats are the places whereupon appear the tubercles 



* This is the Miliary Ulceration described at page 169. 



t One reason for which is the nature of the (mucous) tissue in which they 

 are seated, very different from the cutis vera under disease. — Author. 



I T have often observed this puckered, radiated cicatrix : indeed, I have 

 preserved several specimens of it as proofs that there are occasions on which 

 glanderous chancres heal up. — Author. 



