290 NATURE Ol- GLANDERS. 



and the variously disposed tubercular masses ; the regions, in fact, 

 in which exist the greatest number of lymphatics. This form (of 

 the disease) is always marked by acute symptoms, and by lesions 

 spreading over the membrane of the nose, sinuses, larynx, and 

 sometimes trachea as well. And it is either accompanied or pre- 

 ceded by complete alteration of the fluids; the effects of which are 

 very evident on a number of organs, in particular on the mem- 

 branes of the nose, the sinuses, and the larynx. Very extensive 

 ecchymoses take place in the mucous membranes and fibrous tis- 

 sues underneath the nasal cavities ; and these haemorrhages are, on 

 occasions, followed by destruction of the ecchymosed tissues." 



" The Lymphatic Glands, those in particular receiving the 

 lymphatics from the affected parts, are larger than in their natural 

 condition, softer in substance, and paler {hlafardes), and contain 

 little yellowish white masses, the transformations, probably, of the 

 altered lymphatic fluid. In some cases this liquid appears to be 

 infiltrated into the tissue of the gland, in others, to be accumulated 

 in little sacs," &c. 



" T have met with tubercles, or rather deposits of albuminous 

 substance, in the glands of horses affected with all kinds of glanders 

 and farcy. But these deposits are by no means infallible signs of 

 the ckronicity of the disease. And this is a point I wish to lay 

 stress upon, since it seems to correct an error which by many, as 

 well as by myself, has been long entertained." 



" In glanders and farcy, the lesions we have denominated tuber- 

 culous in the glands, are found within the lungs, the liver, the spleen, 

 the testicles, Sec. And, moreover, I have observed, in respect to 

 the lungs, that the tuberculous growths exist in greater numbers, 

 and become farther developed, than in any other organ. And I 

 therefore think that the respiratory passages are the especial seat 

 of the transmission of glanders; and that they likewise have the 

 greatest influence in generating the spontaneous disease. Glan- 

 derous pulmonary tubercles are exceedingly abundant wherever 

 lymphatics are most numerous." 



" The pulmonary granulations met with in glanders and 

 farcy bear great resemblance to the encysted tubercles of the lym- 

 phatic glands. They are often found in numberless abundance in 



