NATURE OF GLVxNDERS. 207 



That constitutional Disorder accompanies or speedily 

 follows that which, to the superficial observer, has the appearance 

 of being but a local disease — a disease confined, as Lafosse thought, 

 to the nose — has been shewn in our account of the symptoms* ; 

 and that such disorder originates out of the infection of the system, 

 the same as signs of ill health, slight or severe, arising after inocu- 

 lation of the human subject for small or cow-pox, proclaim the con- 

 stitutional efficacy of the inoculation, to me appears highly probable. 

 In cases where glanders or farcy has been the prodTict of inocula- 

 tion, it is possible such constitutional disorder may not be observ- 

 able; and this may have led Leblanc to believe that '' horses that 

 become glandered and farcied without this premonitory disorder 

 derive the disease from contagiont." In the cases, however, of the 

 horses of my own regimentj, which I cannot ascribe to any other 

 source but contagion, the same constitutional disorder was mani- 

 fest; and this is a circumstance which precludes me from as- 

 senting to Leblanc's inference, further than that, in the case of 

 absolute inoculation, such disorder may not, as I said before, be 

 detectible. 



The Eruption of the Disease in some other Part of the 

 body is pretty satisfactory evidence that the virus or infection has 

 travelled from the head through the system into the limbs, or 

 into whatever other part of the body may happen to prove the 

 seat of eruption. Even supposing the contagion or infection from 

 without to be imbibable by the skin as well as by the aerial 

 membrane, the natural conclusion still is, that the former, in a 

 horse already glandered, received its infection through the medium 

 of the constitution. Lastly, we come to that irrefragable proof of 

 the constitutional nature of glanders and farcy afforded by 



Transfusion of the Blood, from out of the vessels of ahorse 

 affected with glanders or farcy, or both, into those of a horse free 

 from any such disease, and the production thereby of the disease 

 — glanders or farcy or both — in the latter subject. That such an 

 experiment has been made on more occasions than one at the Vete- 

 rinary College, in the time of the professorship of Coleman, is well 

 known to many members of the profession now living, several of 



* At page 162. t '^t. page \(^o. '\ At page 230. et sequent. 



