THERAPEUTIC TREATMENT OF GLANDERS. 343 



since, Mr. Ions, V.S., Waterford, has recorded an extraordinary 

 case, in the person of his own son, in confirmation of the good 

 effects of creosote. His son had been unwell from " a severe 

 cold," attended by swollen tonsils and a small sore within the 

 right nostril. While in this state he had occasion to examine a 

 horse with acute glanders. The horse snorted his nasal discharge 

 in his (son's) face. He wiped it with his handkerchief. This was 

 followed by his feeling very unwell, his nose becoming obstructed 

 through a profuse ropy glairy discharge, and his right eye slightly 

 affected. Next, a large ulcer appeared upon the nasal membrane. 

 The disease soon assumed a most alarming character. Mr. Ions 

 urged the trial of creosote. It was conceded to. An ointment, com- 

 posed of one drachm of creosote and seven of lard, was ordered, 

 the slightest application of which produced such agonizing pain 

 that it was immediately discontinued. Mr. Ions was determined 

 it should be persevered with. There was now profuse nasal dis- 

 charge having a most offensive smell, and, to all appearance, 

 universal ulceration, with constitutional symptoms indicative of 

 approaching death. Mr. Ions added two minims of creosote to an 

 ounce of water, and injected the mixture up the nose. After the 

 third injection almost a magical effect took place : the discharge 

 all but ceased, and two days afterwards the ulcers commenced 

 healthy action, and went on rapidly improving. They lost their 

 chancrous character, and assumed a healthy granulating aspect. 

 His diet was nutritious, but no solid food was allowed him. " He 

 drinks a tumbler of good ale every day, and yesterday rode for an 

 hour"*. 



Supposing the disease to be seated within the nasal meatus, 

 there is no more effectual way of applying the injection than 

 through the nostril, with a syringe having a flexible tube of some 

 length affixed to its nozzle, which tube may at pleasure be intro- 

 duced either into the lower or upper meatus, and carried far up the 

 nose or not, according to circumstances. Should it be our object 

 to inject the sinuses, those cavities, of course, must be opened 

 either by means of a small trephine or a bone-gimlet: injections 

 into the frontal sinuses will run into the nasal and maxillary 



* VliTERlNAKlAN for 1 H48 



VOL. III. Y Y 



