1 78 PHYSIC 



dermal tissues respectively, manifests itself as structural 

 exaggeration, but on and within the normal lines of natural 

 histological arrangement and development. Thus the arm 

 of the blacksmith and the whole muscular physique of 

 the athlete undergo trophic increase exclusively along the 

 naturally existent lines of histological continuity and 

 developmental evolution of neuron and muscle fibre, 

 determined by voluntarily increased neuro-dynamic dis- 

 charge and insulated circulation of neuro-plasm or nerve 

 matter and energy, whereby, by repetition, the constantly 

 accentuated supply of neuro-muscular protoplasm becomes 

 "piled up," as it were, in the muscle discs at the terminal 

 extremities of the actively vehicular nervature, with the 

 result that local or general hypertrophy is evolved in the 

 "upper limb" of the former, and the fully developed 

 " classic style " in the latter. Moreover, it may be claimed 

 that the "horny handed" brotherhood of labour display 

 on the same natural lines of evolutionary development 

 the exaggerated dispatch and assimilation of neuro-dermal 

 plasma, and its local ' ' piling up " or storage, amid the 

 dermal structure and appendages of their much exercised 

 manual "organs" or extremities, all which shows once 

 more the truth of the old aphorism, ubi stimulus ibi 

 flux us, and its applicability to the explanation of neuro- 

 muscular and neuro-dermal circulatory and nutritionary 

 phenomena in their absolutely physiological condition ; 

 and foreshadows its corresponding applicability to the 

 decipherment of related pathological phenomena ; further- 

 more, we claim that underlying what we have here 

 advanced are alone, or almost alone, the great principles 

 of the neuro-plasmic material circulation and the neuro- 

 dynamic or force regulation, or the formative disposal of 

 neuro-dermal plasma in the normal or physiological aspect 

 of the subject, the pathological aspect of it emerging by 

 continuity from the physiological. Systemic musculo- 

 dermic, as distinguished from sympathetic structural, 

 textural, or organic degeneration, follows as a pathological 

 phenomenon from a lapse or modification of the physio- 

 logical control of the formative or organic impulses, and 

 the consequently irregular plasmic dispositions of the 

 neuro-muscular and neuro-dermic organic materials on the 



