INFECTIOUS TRACHJTIS 49 



dark pinkish-white in color, and of a parboiled consistency; the bronchi 

 V, ere congested and hemorrhagic up to the syrinx; the trachea, larynx, 

 and pharynx were normal; there was fatty degeneration of the liver and 

 hemorrhagic inflammation of the kidneys, with deposition of urates in 

 the abdominal cavity. This was the first case observed in these experi- 

 ments in which the bronchi were affected. The light in the brooder was 

 accidentally turned off and the bird developed broncho-pneumonia, in addi- 

 tion to infectious trachitis. Apparently bronchitis is a symptom of bron- 

 cho-pneumonia. 



Chicken V 2239. — At necropsy a thick, cheesy pseudomembrane was 

 found occluding the larynx. The anterior half of the trachea was muco- 

 purulent, while the posterior part was normal. The liver and kidneys 

 were slightly swollen and congested. This case was more typical of in- 

 fections trachitis than the former. 



Cliicken ^' 2238. — Tlie carcass showed no marked indications of loss 

 of flesh. The trachea and larynx were hemorrhagic. The blood in the 

 heart and large arteries was unclotted and dark in color. Also the sides 

 of the cage were stained with small specks of blood which had been ex- 

 pelled by coughing and sneezing. Fatty degeneration of the liver was 

 present. The kidneys were hemorrhagic, especially in the tubular areas. 

 The cut surface of the tubules appeared swollen and dark red in color, 

 while the interstitial portion was almost white. The parenchyma and in- 

 terstitial tissues were clearly differentiated in the kidneys. The spleen 

 was congested and of a darker hue than normal for chickens. 



Chicken V 2244. — The gross pathology was typical of the New Jersey 

 strain of infectious trachitis. Tiiis virus appeared to produce more hemor- 

 rhagic symptoms than either the Massachusetts or California strains. 



Chicken V 224.3. — The gross pathology was similar to the findings in 

 the case of V 2244, except that there was an abundance of pseudomem- 

 brane in the larynx and trachea. Prominent lesions noted in other parts 

 of the body were unclotted blood in tiie heart and large arteries, petechiae 

 on tlie pericardium, congestion of tiie liver, henu)rrhages in the tubules 

 of the kidneys, and blanching of the interstitial layers of the same. 



Chicken V 22.50. — The general condition was good. A few patches of 

 pseudomembrane were found in the larynx and trachea. Coagulation 

 necrosis and fibrinous inflammation were evident in the mucosa of the 

 trachea. Some of tlie blood in the heart, large arteries, and veins was 

 unclotted, although the chicken had been in the ice box for twenty-four 

 hours before postmortem examination. The kidneys were hemorrhagic 

 and the blood remained unclotted in the tubular spaces. 



Chicken V 22.51 did not react to the treatment. 



In these experiments the first New Jersey strain of infectious trachitis 

 was carried through five transfers covering a period of 22 days. During 

 this time the virus showed no signs of deterioration. Excluding V 22^51, 

 which resisted infection, the average period of incubation was three days, 

 while the average length of course was eight days. The shortest period of 

 course was three days in two cases, and the longest period was thirty 

 days in one case. 



