30 MASS. KXPI'.RIMENT STATION BULLETIN 308 



10. This cell was found liuariiiig ner\es eind niiiscular and visceral tissues by 

 metastatic and direct intiltr.uion. in incipient cases it first appeared in the 

 capillary spaces and dcstro>ed the nerve fillers and interstitial tissues by utilizing 

 the nourishment for the organization of a tumor. 



11. Evidence is presented which indicates that incipient hmphocytomatosis 

 and neurohnijihomatosis are due to the irritating action of foreign bodies intro- 

 duced into the peritoneal cavit\' and tissues. Since bacteria were isolated 

 only from cases in which jieritonitis was manifest, the inciting agent is not always 

 bacterial. 



12. Attempts to demonstrate the presence of a filtrable \irus in neurohm- 

 phomatosis and lymphocytomatosis in these experiments failed. 



13. Neurohmphomas were most commonK- found in the sciatic, vagus, 

 brachial, celiac, optic, and mesenteric nerves; and h mphocytomas were usually 

 located in the ovar\-, mesentery, ki(lne\'. li\er, spleen, muscle, and skin. 



14. No evidence was found in these studies to indicate that coccidiosis was 

 in an\' way related to either neurohmphomatosis or hmphocytomatosis. 



15. Because of irregularities in the hematolog>- of birds affected with neuro- 

 hmphomatosis, blood counts were of little assistance in removing diseased birds 

 from affected flocks. 



16. On the basis of the experimental data secured in these studies neuro- 

 hmphomatosis and lymphocytomatosis ma\ be controlled b\- eradicating affected 

 birds from the flock as soon as noticed, adopting the best sanitary procedures 

 and increasing the vigor of the birds In- judicious breeding. 



References 



1933. Bieh', J., \ . E. Palmer, and E. A Lloyd. Fowl parahsis (neuro!\-mpho- 



matosis gallinarum). \'et. Jour. 89 (10): 437-440. 

 1928. Blain, D. A study of the white blood cells of the domestic fowl b>' the 

 supravital technique. Anat. Rec. 39 (2): 285-291. 



1928. Breusch, E. Beitrage zur Blutmorphologie des Huhnes. Ztschr. 



Iiffectionskrank. u. Hyg. Haustiere 33: 219-227. 



1917. Burnett, H. B. The clinical pathology of the blood of domesticated ani- 



mals. Textbook: 54-55. Macmillan Co., New York. 



1934. Cook, F. \\'., and R. S. Dearstyne. Hematolog>- of the fowl. (A) Studies 



on normal avian blood. N. C. Agr. Expt. Sta. Tech. Bui. 44: 3-26. 



1932. Fernstermacher, R. Studies of leukemia of fowls. Jour. Amer. \'et. 



Med. Assoc. 80 (N. S. 33) 5: 791-799. 



1929. Forkner, C. E. Blood and bone marrow cells of the domestic fowl. 



Jour. Expt. Med. 50 (1): 121-141. 



1931. Furth, ]. Obser\ ations with a new transmissible strain of leucosis 



(leucemia) of fowls. Jour. Ex{)t. Med. 53 (2): 243-267. 



1933. Furth, J. L\ ni[)homatosis, nnelomatosis, and endothelioma of chickens 



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 Expt. Med. 58 (3): 253-275. 



1918. Graham, G. -S. Benzidine as a peroxidase reagent for blood smears and 



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1932. Johnson, E. P. A study of hnii)honiatosis of fowls (fowl parahsis). 



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