CRYPTOCOCCUS DE GOTTI AND BRAZZOLA 351 



CRYPTOCOCCUS PLIMMERL Costantin * 



This yeast was encountered by Plimmer 2 in a large number of 

 cancers. The cells are round (4 to 40 fj,) with a double membrane. 

 The cells may be isolated or united to the number of from two to 

 sixty. 



On liquid media (2% glucose broth and 1% tartaric acid) it forms 

 a deposit at the end of a few days. On gelatin added to the same 

 bouillon the growth is feeble with no liquefaction. On agar added to 

 the same liquid the colonies are small, isolated, slightly rounded, 

 white in the beginning and yellow in old cultures. On potato the 

 yeast develops a thick layer, at first white and after a time a brownish 

 yellow. This yeast is pathogenic for guinea pigs only on intraperi- 

 toneal injection. 



CRYPTOCOCCUS CORSELLII (Corselli and Frisch). 

 Neveu-Lemaire 



Isolated by Corselli and Frisch 3 from a sarcoma in the mesenteric 

 ganglions of a man, this yeast possesses black cells of variable di- 

 mensions, slightly rounded, and agglutinated in masses. It is easily 

 cultivated on gelatin, agar, dextrose, broths, sugar jellies, neutral or 

 alkalin. It possesses a very feeble power of fermenting, and shows a 

 pathogenicity for guinea pigs, dogs and rabbits in intraperitoneal 

 injections. 



CRYPTOCOCCUS DE GOTTI AND BRAZZOLA 



Syn.: ATELOSACCHAROMYCES DE GOTTI AND BRAZZOLA. De 

 Beurmann and Gougerot 



Discovered by Gotti and Brazzola 4 in a myxosarcoma of the nasal 

 passages of a horse, this yeast possesses cells of variable dimensions, 

 round or slightly oval, with granular contents surrounded by a double 

 membrane and a mucilaginous capsule, sometimes stratified. 



In bouillon it produces clumps and on gelatin stabs a train of 

 clumped masses with indented edges. On gelatin plates the colonies 



1 Costantin, Les levures des animaux, Bull, de la Soc. mycologique de France, 

 v. XVII. 1901. 



2 Plimmer, Vorlaiifige Notiz iiber Gewisse von Krebse isolierle Organismen 

 und deren pathogene Wirkung in Thieren, Centr. f. Bakt., v. XXV, 1899. 



3 Corselli, G., and Frisch, B. Blastomiceti pathogene nell'uomo. Annali 

 d'Igiene sperim., v. V, 1895, and Centr. f. Bak. v. XVIII, 1895. 



4 Gotti and Brazzola, Sopra un caso di blastomicosi nasale in una cavalla. 

 Memorie d. R. Ac. d. Scienze di Bologna, v. VI, 1897. 



