348 



PATHOGENIC YEASTS 



media, the cells became round or oval and were surrounded by a 

 double membrane. Whether the parasite reproduced by budding or 

 not seemed to be independent of aerobiosis. 



CRYPTOCOCCUS FARCIMINOSUS. Rivolta and Micellone 



Syn.: SACCHAROMYCES EQUI. Marcone. CRYPTOCOCCUS RIVOLTAE. 

 Fermi and Aruch. PARENDOMYCES DE RIVOLTA AND MICELLONE. 

 De Beurmann and Gougerot 



This species has been regarded as the causal organism 

 of glanders which attacks horses and mules. It has round 

 or oval cells, sometimes pointed at the poles, with 

 granular contents (Fig. 149). It is easily cultivated in 

 all media. On potato, it produces a round, raised colony 

 with a dirty white color. It scarcely develops on agar. 

 Fermi and Aruch l have described in the cells of this yeast 

 found in pus, globules which 

 they regarded as ascospores. 

 These could not be found in 

 artificial cultures, however. 



oo 



Fig. 149. 

 Crypt, far- 

 dminosus. 

 Growth of 

 Cells and 

 Ascs in the 

 Pus (after 

 Fermi and 

 Aruch) . 



CRYPTOCOCCUS HOMINIS (Busse). 

 Vuillemin 



Syn.: ATELOSACCHAROMYCES HOMINIS. 

 De Beurmann and Gougerot 



Discovered by Busse, 2 in chronic periostitis 

 of the tibia, this yeast, in situ, possesses cells 

 which are round or oval, unites in various 

 numbers in a substance with a homogeneous 

 appearance, making a sort of common cap- 

 sule. (Fig. 150, B.) In cultures, the same 

 shape is presented but there is no homo- Fig. 150. Cryptoc. hominis. 

 geneous substance. There is a membrane A . ow Culture on Prune Juice. 

 with a double layer which thickens as the 

 culture becomes older. (Fig. 150, A.) It is 

 cultivated easily on all media between 15 and 38 C. In liquid media 

 a sediment is formed and on prune juice it finally forms a scum 

 with a dirty gray color. In gelatin stabs, the colonies are white and 



1 Fermi, C., and Aruch. Ueber eine neue pathogene Hefeart und iiber die 

 Natur des sogennanten Cryptococcus farminosus, Rivolta. Cent. Bakt. 17, 1895. 



2 Busse, Ueber Saccharomyces hominis. Virchow's Archive, 40, 1895. 



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