CRYPTOCOCCUS LITHOGENES 349 



shiny but there is no liquefaction. On potato, the colonies soon unite 

 to form a thick dirty white layer. This yeast ferments dextrose. 

 It is pathogenic for rabbits, white rats and dogs. 



CRYPTOCOCCUS LINGUAE-PILOSAE. Vuillemin 

 Syn. SACCHAROMYCES LINGUAE-PILOSAE. Raynard and Lucet 



This yeast was discovered by Raynard and Lucet in a sickness 

 called black tongue. Lucet who has studied this disease experi- 

 mentally has shown that it may not be reproduced. According to 

 Guegen l and Thaon, 2 this yeast acts only in 

 association with Oospora lingualis. There 

 seems to be a sort of symbiotic association 

 between these two fungi. This yeast has 

 round or oval cells, often elongated, in which 

 the buds often remain united to the mother 

 cell. This gives the appearance of a pseudo- 

 mycelium. (Fig. 151.) On glucose, levulose, A . Ce ii s developed on Scum in 

 glycerol and especially potato decoctions, ^&^u^*S> 

 or fruit decoctions, after 10 hours at 37 C., 



there is good growth. Later the scum thickens and becomes gray or 

 reddish. It may also become folded with a ring. On gelatin this 

 yeast forms a mucous layer, white, shining, with contours. On potato 



it forms a thin layer, dry and brown. The 



optimum temperature for budding is found 



between 25 and 35. 



This yeast ferments glucose and levulose. 



It is pathogenic for animals. 

 V 



7 



Fig. \b2.-Cryptococcus CRYPTOCOCCUS LITHOGENES. Vuillemin 



lithogenes. 



2 to 4. Young Cells. -5 to 6. ty 71 "' SACCHAROMYCES LITHOGENES. San FellCC 

 Cells which have Undergone . . 



a chalky Degeneration (after This yeast was discovered by San Felice 3 



San Felice). , J J ' . 



in the lymphatic ganglions of a cow which 



died from generalized carcinoma. In the animal it possesses round 

 cells of variable forms and dimensions, sometimes enclosed in a 

 calcified capsule, with brilliant granules in the protoplasm (Fig. 152). 



1 Guegen, F. Sur Oospora lingualis et Cryptococcus linguae-pilosae. Arch. 

 de parasitol. 12, 1909. 



2 Thaon, P. Symbiose de levure et oospora dans un cas de langue noire, 

 "oc. de Biol. 67, 1909. 



3 San Felice, F. Ueber eine fur Thierpathogene Sprosspilzart und iiber die 

 morph. Uebereinstimmung welche sie bei ihren Vorkommen in den Gesseln mit 

 Krebsascidien zeigt. Centr. f. Bak., V. XVII. 1895. 



