CRYPTOCOCCUS DE GOTTI AND BRAZZOLA 351 



CRYPTOCOCCUS PLIMMERI. Costantin 1 



This yeast was encountered by Plimmer 2 in a large number of 

 cancers. The cells are round (4 to 40 ju) with a double membrane. 

 The cells may be isolated or united to the number of from two to 

 sixty. 



On liquid media (2% glucose broth and 1% tartaric acid) it forms 

 a deposit at the end of a few days. On gelatin added to the same 

 bouillon the growth is feeble with no liquefaction. On agar added to 

 the same ' liquid the colonies are small, isolated, slightly rounded, 

 white in the beginning and yellow in old cultures. On potato the 

 yeast develops a thick layer, at first white and after a time a brownish 

 yellow. This yeast is pathogenic for guinea pigs only on intraperi- 

 toneal injection. 



CRYPTOCOCCUS CORSELLH (Corselli and Frisch). 

 Neveu-Lemaire 



Isolated by Corselli and Frisch 3 from a sarcoma in the mesenteric 

 ganglions of a man, this yeast possesses black cells of variable di- 

 mensions, slightly rounded, and agglutinated in masses. It is easily 

 cultivated on gelatin, agar, dextrose, broths, sugar jellies, neutral or 

 alkalin. It possesses a very feeble power of fermenting, and shows a 

 pathogenicity for guinea pigs, dogs and rabbits in intraperitoneal 

 injections. 



CRYPTOCOCCUS DE GOTTI AND BRAZZOLA 



Syn.: ATELOSACCHAROMYCES DE GOTTI AND BRAZZOLA. De 

 Beurmann and Gougerot 



Discovered by Gotti and Brazzola 4 in a myxosarcoma of the nasal 

 passages of a horse, this yeast possesses cells of variable dimensions, 

 round or slightly oval, with granular contents surrounded by a double 

 membrane and a mucilaginous capsule, sometimes stratified. 



In bouillon it produces clumps and on gelatin stabs a train of 

 clumped masses with indented edges. On gelatin plates the colonies 



1 Costantin, Les levures des animaux, Bull, de la Soc. mycologique de France, 

 v. XVII. 1901. 



2 Plimmer, Vorlaiifige Notiz iiber Gewisse von Krebse isolierle Organismen 

 und deren pathogene Wirkung in Thieren, Centr. f. Bakt., v. XXV, 1899. 



3 Corselli, G., and Frisch, B. Blastomiceti pathogene nelPuomo. Annali 

 d'Igiene sperim., v. V, 1895, and Centr. f. Bak. v. XVIII, 1895. 



4 Gotti and Brazzola, Sopra un caso di blastomicosi nasale in una cavalla. 

 Memorie d. R. Ac. d. Scienze di Bologna, v. VI, 1897. 



