ATELOSACCHAROMYCES HARTERI 359 



It does not ferment dextrose or maltose. It is pathogenic for mice, 

 less pathogenic for rats, guinea pigs, rabbits and dogs. Intraperi- 

 toneal injection causes fatal septicemia in mice. 



ATELOSACCHAROMYCES OF BREWER AND WOOD 



De Beurmann and Gougerot 



This yeast was isolated by Brewer and Wood from a human 

 blastomycosis. In situ the cells are spherical (10-25 fjc in diameter) 

 and are surrounded by a large mucilaginous capsule. In culture no 

 filaments are formed, but the cells sometimes remain united in short 

 chains in old cultures. On glycerol agar the growth is small and gives 

 grayish white colonies. On agar plates development is very abun- 

 dant on the surface in a creamy yellow mass. On potato growth is 

 difficult. On gelatin there is no liquefaction. The species grows 

 difficultly in liquid media and produces no fermentation. 



ATELOSACCHAROMYCES HARTERI (Harter 2 ) 

 De Beurmann and Gougerot 



This yeast was isolated by Harter from a generalized human 

 saccharomycosis. The cells are oval or elliptical, rather spherical 

 (4-6 /z by 3-5 (JL). On solid media and on Raulin's solution sometimes 

 elongated units are observed, but never filaments, properly speaking. 



On old cultures on carrot certain cells become round and very 

 voluminous (5-8 /^ in diameter). These are probably durable cells or 

 chlamydospores. 



The yeast grows well at 37 at laboratory temperatures. The 

 growth ceases, however, at about 10. The cells withstand 55, but 

 are killed in a quarter of an hour at 65 in moist condition. 



On gelatin development is small and less abundant, white, granu- 

 lar, and penetrating into the medium with arborescent structure. 

 There is no liquefaction on gelatin. On 1% glucose gelatin develop- 

 ment is a little more abundant. On plain agar development is feeble 

 and slow. On glycerol gelatin there is abundant growth with a pro- 

 duction of a downy appearance at depths. On glucose or maltose 

 agar there is abundant development of a white, creamy growth. On 

 blood serum there is very meager growth. On carrot there is abun- 

 dant development, quickly covering the whole surface with a creamy, 

 white, thick, granular layer. On potato growth is grayish white, dry 

 and not very abundant. The yeast inverts saccharose very slightly, 

 but does not give any fermentation. 



1 Brewer and Wood, C., Blastomycosis of the spine. Annals of Surgery, 1908. 



2 Harter, G., De la blastomycose humaine. These de medecine. Nancy, 

 1909. 



