252 RETROGRADE SECT. XXIX. 4. 9. 



26. Water reduced to fourteen pints. 



28. Water thirteen pints : he continues the opium,, and 

 takes four fcruples of the refin for a dofe. 



February i. Water twelve pints. 



4. Water eleven pints : twitchings lefs ; takes five fcruples 

 for a dofe. 



8. Water ten pints : has had many (lools. 



12- Appetite lefs: purges very much. 



After this the refin either purged him, or would not flay on 

 his fiomach : and he gradually relapfed nearly to his former 

 condition, and in a few months funk under the diieafe. 



Odober 3, Mr. Hughes evaporated two quarts of the water, 

 and obtained from it four ounces and half of hard and brittle 

 faccharine mafs, like treacle which had been fometime boiled. 

 Four ounces of blood which he took from his arm with defign to 

 examine it, had the common appearances, except that the fe- 

 rum refembled cheefe-whey ; and that on the evidence of four 

 perfons, two of whom did not know what it was they tafted, the 



ferum had a faltifb tfifte. 

 j j j */ 



From hence it appears, that the faccharine matter, with which 

 the urine of thefe patients fo much abounds does not enter the 

 blood-veflels like the nitre and afparagus mentioned above ; but 

 that the procefs of digeftion refembles the procefs of the ger- 

 mination of vegetables, or of making barley into malt ; as the 

 valt quantity of fugar found in the urine muft be made from 

 the food which he took (which was double that taken by others), 

 and from the fourteen pints of fmall beer which he drank. And, 

 fecondly, as the ferum of the blood was not fweet, the chyle ap- 

 pears to have been conveyed to the bladder without entering the 

 circulation of the blood, fince fo large a quantity of fugar, as 

 was found in the urine, namely twenty ounces a day, could not 

 have previoufly exifled in the blood without being perceptible to 

 the taite. 



November i Mr. Hughes difTblved two drams of nitre in a 

 pint of a*!ecolion of the roots of afparagus, and added to it two 

 ounces of tindlure of rhubarb: the patient took a fourth part 

 of this mixture every five minutes, till he had taken the whole. 

 In about half an hour he made eighteen ounces of water, 

 which was very manifeflly tinged with the rhubarb , the fmell 

 of afparagus was doubtful. 



He then loft four ounces of blood, the ferum of which was 

 not fo opaque as that drawn before, but of a yellowifh caft, as 

 the ferum of the blood ufually appears. 



Paper dipped three or four times in the tinged urine and dri- 

 ed again, did not fcintillate when is was fet en fire : but when 



the 



