54 EFFECTS OF 



minutes from the second application respiration 

 had entirely ceased, and she was apparently 

 dead. On opening the thorax, I found the heart 

 acting with regularity and strength, circulating 

 dark-coloured blood. I introduced a tube into 

 the trachea, and produced artificial respiration. 

 The contractions of the heart became augmented 

 in force and frequency, and there was no evident 

 diminution in six or seven minutes, during which 

 the artificial respiration was continued. 



On dissection, nothing remarkable was found 

 in the appearance of the tongue or brain. 



The symptoms and mode of death in this ex- 

 periment did not essentially differ from those 

 produced by the essential oil of almonds. I was 

 surprised to find the effects of the empyreumatic 

 oil so entirely different from those of the infusion 

 of tobacco. Supposing that this difference might 

 arise from the poison being more concentrated 

 in the oil than in the infusion, I made the follow- 

 ing experiments. 



EXPEKIMENT XIV. 



A drop of the oil of tobacco was suspended in 

 an ounce and a half of water, by means of muci- 

 lage of gum arabic, and the whole was injected 

 into the rectum of a dog. In two minutes after- 

 wards he became faint, retched, but did not 

 vomit. He appeared to be recovering from this 

 state, and in 25 minutes after the first injection, 

 it was repeated in the same quantity. He was 



