CONTENTS 7 



PAGE 



CHAPTER XXVI. THE RELATION OF COLLOIDS AND LIPOIDS TO IMMUNITY. . . . 511 



Kinds of colloids, 511 Nature and properties of colloids, 511 Analogy be- 

 tween the reactions of immunity and those of colloidal chemistry, 515 Anti- 

 toxins, 516 Agglutinins and precipitins, 517 Hemolysins, 518 Complement 

 fixation as a colloid reaction, 519 The relation of lipoids to immunity, 520 

 The epiphanin reaction, 522 The miostagmin reaction, 526. 



CHAPTER XXVII. ANAPHYLAXIS 531 



Historic, 532 Definition, 535 Phenomena of anaphylaxis, 536 Mechan- 

 ism of anaphylaxis, 541 Anaphylactogens or allergens, 543 Anaphylatoxin, 

 548 Anaphylactin (allergin), 552 Theories of anaphylaxis, 556 Passive 

 anaphylaxis, 559 Anti-anaphvlaxis, 561 Specificity of anaphylaxis, 563. 



PART IV 



APPLIED IMMUNITY IN THE PROPHYLAXIS, DIAGNOSIS, AND TREAT- 

 MENT OF DISEASE SPECIFIC THERAPY 



CHAPTER XXVIII. ANAPHYLAXIS IN ITS RELATION TO INFECTION AND IM- 

 MUNITY. ANAPHYLACTIC OR ALLERGIC REACTIONS 565 



Relation of anaphylaxis to infectious diseases, 566 Relation of anaphylaxis 

 to non-infectious diseases, 570 Serum disease, 571 Idiosyncrasies, 577 

 Relation of anaphylaxis to immunity, 580 Anaphylactic or allergic reactions, 

 582 Subcutaneous tuberculin reaction, 592 Intracutaneous tuberculin re- 

 action, 595 Cutaneous tuberculin reaction, 596 Conjunctival tuberculin re- 

 action, 598 Percutaneous tuberculin reaction, 599 Tuberculin reactions 

 among the lower animals, 600 The luetin reaction, 601 The mallein reaction, 

 606 Allergic reactions in typhoid fever, 607 Allergic reactions in other dis- 

 eases, 609 Allergic reactions as a measure of immunity, 610. 



CHAPTER XXIX. ACTIVE IMMUNIZATION. VACCINES IN THE PROPHYLAXIS 



AND TREATMENT OF DISEASE. VACCINE THERAPY 611 



Historic, 611 Nomenclature, 613 Method of preparing vaccines, 614 

 Mechanism of active immunization, 616 Living versus dead vaccines, 620 

 Sensitized vaccines, 620 Autogenous versus stock bacterial vaccines, 620 The 

 negative phase, 621 Contraindications to active immunization, 622. Prophy- 

 lactic Immunization or Vaccination, 623 In small-pox, 623 In rabies, 636 In 

 typhoid fever, 643 In plague, 647 In cholera, 650 -In dysentery, 652 In 

 cerebrospinal meningitis, 652 In scarlet fever, 652 In anthrax, 653 In 

 black-leg, 655. Therapeutic Immunization. Bacterial Vaccine Therapy, 655 

 Principles, 655 Diseases of the skin, 656 Diseases of the genito-urinary system, 

 657 Diseases of the respiratory system, 659 Acute general infections, 660 

 Tuberculin therapy, 661. 



CHAPTER XXX. PASSIVE IMMUNIZATION. SERUMS IN THE PROPHYLAXIS AND 



TREATMENT OF DISEASE. SERUM THERAPY 681 



Definition, 681 Purposes of passive immunization, 682 Kinds of passive 

 immunity, 683 Indications for passive immunization, 684^Contraindications 

 to passive immunization, 686 Technic of subcutaneous inoculation, 688 

 Technic of intramuscular inoculation, 690 Technic of intravenous inoculation, 



690 Technic of subdural inoculation, 694. Serum Treatment and Prophylaxis 



of Diphtheria, 702. Serum Treatment and Prophylaxis of Tetanus, 719. Se- 

 rum Treatment and Prophylaxis of Dysentery, 730. Serum Treatment and 

 Prophylaxis of Hog Cholera, 732. Serum Treatment of Snake Bites, 733. 

 Serum Treatment and Prophylaxis of Hay-fever, 734. Serum Treatment and 

 Prophylaxis of Meningococcus Meningitis, 736. Serum Treatment of Influenzal 

 Meningitis, 749. Serum Treatment of Pneumococcus Meningitis, 751. Serum 

 Treatment of Other Localized Pneumococcus Infections, 754. Serum Treat- 

 ment of Lobar Pneumonia, 754. Serum Treatment of Streptococcus Infections, 

 760. Serum Treatment of Gonococcus Infections, 765. Serum Treatment of 

 Staphylococcus Infections, 766. Serum Treatment of Anthrax, 767. Serum 

 .Treatment of Typhoid Fever, 768. Serum Treatment of Plague, 769. Serum 

 Treatment of Cholera, 770. Serum Treatment of Tuberculosis, 771. 



