8 CONTENTS 



PAGE 



CHAPTER XXXI. SERUM THERAPY (continued) 772 



Normal Serum Therapy, 772 Serum treatment of hemorrhage, 772 Serum 

 treatment of the toxicoses of pregnancy, 773 Serum treatment of skin diseases, 

 774. Autoserum Therapy, 775-J-Autoserum treatment of skin diseases, 775 

 Autoserum treatment of acute infectious diseases, 775 Autoserum treatment 

 of syphilis (salvarsanized serum), 776 Autoserum treatment of tuberculosis 

 of serous membranes, 781 Autoserum treatment of non- tuberculous effusions, 

 782. 



CHAPTER XXXII. CHEMOTHERAPY 784 



Principles of Chemotherapy, 785 Organotropism and parasitotropism, 785 

 Chemoreceptors, 787 Drug "fastness," 789 Therapia magna sterilisans, 791. 

 Salvarsan and Neosalvarsan in the Treatment of Syphilis, 792 Historic, 792 

 Properties of salvarsan, 794 Properties of neosalvarsan, 795 Methods for pre- 

 paring salvarsan for administration, 795 Methods for preparing neosalvarsan for 

 administration, 795 Administration of salvarsan and neosalvarsan by intra- 

 venous injection, 797 By intramuscular injection, 805 By intraspinous in- 

 jection, 806 Contraindications and precautions in salvarsan therapy, 808 

 Value of salvarsan and neosalvarsan in the treatment of syphilis, 809. Salvarsan 

 in the Treatment of Non-syphilitic Diseases, 810. Chemotherapy in Bacterial 

 Diseases, 811. Chemotherapy in Malignant Diseases, 812. 



PART V 



EXPERIMENTAL INFECTION AND IMMUNITY 



Introductory, 814 Methods, 814 The Student, 814 Records, 815 Animal 



Experiments and Autopsies, 815. 



EXERCISE 1. Active Immunization of Animals, 815. 



Experiment 1, Production of Agglutinins, Bacteriolysins and Opsonins, 815 

 Experiment 2, Production of Precipitins, 816 Experiment 3, Production of 

 Hemolysins, 816 Experiment 4, Production of Cytotoxin, 816. 



EXERCISE 2. Infection, 816. ' 



Experiment 5, Experimental Pneumonia, 816. 



EXERCISE 3. Toxins, 817. 



Experiment 6, Diphtheria Toxin, 817 Experiment 7, Method of Testing the 

 Virulence and Toxicity of Diphtheria Bacilli, 818 Experiment 8, Tetanus Toxin 

 (in vivo), 819 Experiment 9, Tetanus Toxin (in vitro), 819. 



EXERCISE 4. Toxins (continued), 820. 



Experiment 10, Botulism Toxin, 820 Experiment 11, Dysentery Toxin, 820^- 

 Experiment 12, Staphylotoxin (in vivo), 821 Experiment 13, Staphylotoxin 

 (in vitro), 821. 



EXERCISE 5. Toxins (continued) Plant and Animal Toxins, 822. 



Experiment 14, Streptotoxin, 822 Experiment 15, Phytotoxins (in vivo and 

 in vitro), 822 Experiment 16, Zoo toxin, Cobra venom (in vivo and in vitro), 823. 



EXERCISE 6. Endotoxins and Aggressins, 823. 



Experiment 17, Endotoxins, 823 Experiment 18, Natural Aggressins, 824. 



EXERCISE 7. Bacterial Protein. Ptomains. Mechanical Action of Bacteria, 824. 

 Experiment 19, Bacterial Protein, 824 Experiment 20, Ptomains, 825 Ex- 

 periment 21, Mechanical Action of Bacteria, 826. 



EXERCISE 8. Kinds of Immunity. Natural Immunity, 826. 



Experiment 22, Phagocytosis in Natural Immunity, 826 Experiment 23, Nat- 

 ural Antibacterial Immunity, 826 Experiment 24, Relative Factors in Natural 

 Immunity, 827 Experiment 25, Influence of Temperature Upon Natural 

 Immunity, 827. 



EXERCISE 9. Acquired Immunity, 827. 



Experiment 26, Acquired Active (Antibacterial) Immunity, 827 Experiment 

 27, Acquired Passive (Antitoxic) Immunity, 828 Experiment 28, Acquired 

 Passive (Antitoxic) Immunity, 828 Experiment 29, Acquired Passive (Anti- 

 bacterial) Immunity, 828. 



